Doxofylline Impurity 13 CAS 43135-57-5
| CAS No. | 43135-57-5 |
| Molecular Formula | C13H20N4O4 |
| Molecular Weight | 296.32 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Doxofylline Impurity 13 (CAS 43135-57-5) is a certified pharmaceutical impurity reference standard with the molecular formula C13H20N4O4 and a molecular weight of 296.32 g/mol.
Based on its molecular formula C13H20N4O4, Doxofylline Impurity 13 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 296.32 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Doxofylline Impurity 13 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H20N4O4 |
| Molecular Weight | 296.32 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1969 |
| Nitrogen Atoms | 4 |
Related Doxofylline Standards
- Doxofylline impurity 44 (CAS CATO-C4X-151344)
- Doxofylline Impurity 43 (CAS CATO-C4X-151343)
- Doxofylline Impurity 21 (CAS CATO-C4X-151321)
- Doxofylline Impurity 37 (CAS CATO-C4X-151337)
- Doxofylline Impurity 39 (CAS CATO-C4X-151339)
- Doxofylline Impurity 4 (CAS 2095554-12-2)
- Doxofylline Impurity 49 (CAS CATO-C4X-151349)
- Doxofylline Impurity 41 (CAS CATO-C4X-151341)
Recommended Standards
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