(5-Fluoro-2-(2-methoxyethoxy)pyridin-4-yl)boronic acid CAS 2096341-69-2
| CAS No. | 2096341-69-2 |
| Molecular Formula | C8H11BFNO4 |
| Molecular Weight | 214.99 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of (5-Fluoro-2-(2-methoxyethoxy)pyridin-4-yl)boronic acid (C8H11BFNO4) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
(5-Fluoro-2-(2-methoxyethoxy)pyridin-4-yl)boronic acid (CAS 2096341-69-2) is a high-purity analytical reference standard with the molecular formula C8H11BFNO4 and a molecular weight of 214.99 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (5-Fluoro-2-(2-methoxyethoxy)pyridin-4-yl)boronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H11BFNO4 |
| Molecular Weight | 214.99 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
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- 4-Fluoro-3-Bromoanthranilonitrile (CAS 1093951-76-8)
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Recommended Standards
- (3-Acetyl-5-nitrothiophen-2-yl)boronic acid (CAS 58157-90-7)
- 2-Amino-3-iodopropanoic acid (CAS 62965-18-8)
- 1-Bromo-1,1-difluoropentane-2,4-dione (CAS 164342-73-8)
- 3-Chloro-2,4,5-trifluorobenzyl chloride (CAS 101513-88-6)
- 3-[1-(tert-butoxycarbonylamino)cyclobutyl]prop-2-ynoic acid (CAS 2361635-00-7)
- 3-Amino-3-(3-iodophenyl)propanoic acid hydrochloride (CAS 2137733-50-5)
- 2-(3-Cyclopropyl-1-methyl-1h-1,2,4-triazol-5-yl)propan-1-amine (CAS 1342627-04-6)
- 4-Amino-6-methyl-3-((3-(trifluoromethyl)benzyl)thio)-1,2,4-triazin-5(4H)-one (CAS 869068-01-9)
- 4-(Diethoxyphosphinyl)benzoic Acid (CAS 1527-34-0)
- Obeticholic Acid Impurity 47 (CAS CATO-C4X-115347)
- 4-Aminobicyclo[2.2.2]octane-1-carbonitrile (CAS 135908-50-8)
- 2-Amino-5-(methylsulfonyl)-4-(4-nitrophenyl)thiophene-3-carbonitrile (CAS 1707668-32-3)
- 5-Chloro-4-methoxy-thiophene-3-carbonyl chloride (CAS 175137-49-2)
- Exenatide (CAS 141758-74-9（free base）)
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