4-(t-Butyldimethylsilyloxy)-2,6-difluorophenylboronic acid CAS 2096341-77-2
| CAS No. | 2096341-77-2 |
| Molecular Formula | C12H19BF2O3Si |
| Molecular Weight | 288.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(t-Butyldimethylsilyloxy)-2,6-difluorophenylboronic acid.
4-(t-Butyldimethylsilyloxy)-2,6-difluorophenylboronic acid (CAS 2096341-77-2) is a high-purity analytical reference standard with the molecular formula C12H19BF2O3Si and a molecular weight of 288.17 g/mol.
Structurally, 4-(t-Butyldimethylsilyloxy)-2,6-difluorophenylboronic acid (C12H19BF2O3Si) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 2.5, corresponding to approximately 2 ring(s) or double-bond equivalent(s). With a molecular weight of 288.17 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H19BF2O3Si |
| Molecular Weight | 288.17 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.5 |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F-containing |
Related t Standards
- 5-(t-Butyldimethylsilyloxy)-2,3-difluorophenylboronic acid (CAS 1150114-45-6)
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- 3-t-Butyldimethylsilyloxy-4-chlorophenylboronic acid (CAS 2096337-83-4)
- 1-(tert-butyldimethylsilyloxy)-2-iodoethane (CAS 101166-65-8)
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Recommended Standards
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- Amorolfine Impurity 60 (CAS CATO-C4X-154260)
- Cis 1-Benzyl-4-(4-fluorophenyl)-6-oxopiperidine-3-carboxylic Acid Methyl Ester (CAS 612095-73-5)
- Potassium trifluoro[(3-fluorophenyl)methyl]boranuide (CAS 2126821-95-0)
- 1-(6-(Indolin-1-yl)-4-methylpyridin-3-yl)propan-1-ol (CAS 1355194-51-2)
- 2-(4-Ethylphenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol (CAS 785-98-8)
- 2'-Amino-2,2,2-trifluoro-6'-(trifluoromethyl)acetophenone (CAS 1448858-57-8)
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- 4-Cyclopropoxy-3-methyl-2-(trifluoromethyl)pyridine (CAS 1243287-86-6)
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