5-Chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine CAS 2096998-68-2
| CAS No. | 2096998-68-2 |
| Molecular Formula | C22H36BClN2O2Si |
| Molecular Weight | 434.88 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine.
5-Chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine (CAS 2096998-68-2) is a high-purity analytical reference standard with the molecular formula C22H36BClN2O2Si and a molecular weight of 434.88 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 5-Chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 434.88 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H36BClN2O2Si |
| Molecular Weight | 434.88 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 4-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1045857-94-0)
- 5-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1072152-34-1)
- 5-Chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1073338-95-0)
- benzyl 4-(5-chloro-1-(2-ethoxy-2-oxoethyl)-6-oxo-1,6-dihydropyridazin-4-yl)piperazine-1-carboxylate (CAS 1000018-18-7)
- 2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-N-(3,4-dimethoxyphenethyl)acetamide (CAS 1023543-68-1)
- 5-(3-Chloro-4-fluorophenyl)-3-methyl-3-(pyrimidin-5-ylmethyl)-1-(1H-1,2,4-triazol-3-yl)indolin-2-one (CAS 1141080-15-0)
- 4-(4-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)phenyl)pyrimidin-2-amine (CAS 337919-73-0)
- Ethyl 7-chloro-6-formyl-2-(4-nitrobenzamido)-4,5-dihydrobenzo[b]thiophene-3-carboxylate (CAS 905426-20-2)
Recommended Standards
- 5-Bromo-6-(dibromofluoromethyl)hexahydro-4,7-methanoisobenzofuran-1,3-dione stereoisomer (CAS 21902-82-9)
- N-[(1E)-1-{N'-[(1Z)-(4-chlorophenyl)methylidene]hydrazinecarbonyl}-2-[(4-methylpyrimidin-2-yl)amino]eth-1-en-1-yl]benzamide (CAS 306976-29-4)
- Cefminox Sodium Impurity 20 (CAS 57617-09-1)
- BX 471 (CAS 217645-70-0)
- (3-Amino-4-methoxyphenyl)(morpholino)methanone (CAS 926211-47-4)
- 2,4-Dichloro-5-(trifluoromethyl)pyridine (CAS 888327-38-6)
- 4-Fluoro-2-methylphenyl Chloroformate (CAS 1552201-86-1)
- 6-O-Feruloylsucrose (CAS 137941-45-8)
- 4-Methoxyphenethylmagnesium bromide 0.5 M in Tetrahydrofuran (CAS 36278-54-3)
- 1-(bromomethyl)-1-methoxycyclopentane (CAS 1250243-35-6)
- Semaglutide impurity 50 (CAS 2773558-66-8)
- 5-methyl-N-(propan-2-yl)-1,3,4-thiadiazol-2-amine (CAS 62347-23-3)
- 1-(2-(Benzyloxy)-5-bromophenyl)adamantane (CAS 736992-49-7)
- Tirzepatide Impurity 48 (CAS CATO-C4X-324048)
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