Palbociclib Impurity 23 CAS 2098673-40-4
| CAS No. | 2098673-40-4 |
| Molecular Formula | C24H29N7O3 |
| Molecular Weight | 463.53 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Palbociclib Impurity 23 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Palbociclib Impurity 23 (CAS 2098673-40-4) is a certified pharmaceutical impurity reference standard with the molecular formula C24H29N7O3 and a molecular weight of 463.53 g/mol.
Palbociclib Impurity 23 (C24H29N7O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H29N7O3 |
| Molecular Weight | 463.53 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Nitrogen Atoms | 7 |
Related Palbociclib Standards
- Palbociclib Impurity 186 (CAS 2174002-29-8)
- Palbociclib Impurity 58 (CAS 2231085-26-8)
- Palbociclib Impurity 92 (CAS CATO-C4X-112592)
- Palbociclib Impurity 189 (CAS CATO-C4X-1125189)
- Palbociclib Impurity 147 (CAS 2624141-94-0)
- Palbociclib Impurity 56 (CAS 571189-51-0)
- Palbociclib Impurity 127 (CAS CATO-C4X-1125127)
- Palbociclib impurity 163 (CAS CATO-C4X-1125163)
Recommended Standards
- Tadalafil Impurity 60 (CAS 1588526-67-3)
- Methyltetrazine-PEG4-NH-Boc (CAS 2194563-84-1)
- Baricitinib Impurity 77 (CAS CATO-C4X-226077)
- 4-((2-(2,2-Di(1H-indol-3-yl)ethyl)phenyl)amino)-2-methylene-4-oxobutanoic acid (CAS 6941-74-8)
- Ertapenem Impurity 21 (CAS CATO-C4X-163321)
- Dorzolamide Impurity 22 (CAS 147128-79-8)
- Upadacitinib Impurity 154 (CAS CATO-C4X-2405154)
- N-(3-Methyl-5-styrylisoxazol-4-yl)benzamide (CAS 109300-10-9)
- 3-((4-Chlorobenzyl)sulfonyl)-N-(4-chlorophenyl)-2-hydroxy-2-methylpropanamide (CAS 338424-18-3)
- 1-(4-Chlorobenzyl)-1H-pyrazole-3-carboxylic acid (CAS 1309785-77-0)
- Darolutamide Impurity 14 (CAS CATO-C4X-310614)
- (2E)-N'-(4-Fluorophenyl)-3-(quinolin-3-yl)prop-2-enehydrazide (CAS 478046-44-5)
- (1,3,3-Trimethylcyclohexyl)methanamine hydrochloride (CAS 1363405-49-5)
- Semaglutide impurity 200 (CAS CATO-C4X-2226200)
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