Salicylic Acid Impurity 26 CAS 2100-31-4
| CAS No. | 2100-31-4 |
| Molecular Formula | C10H12O3 |
| Molecular Weight | 180.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Salicylic Acid Impurity 26 (C10H12O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Salicylic Acid Impurity 26 (CAS 2100-31-4, C10H12O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Salicylic Acid Impurity 26 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H12O3 |
| Molecular Weight | 180.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Salicylic Standards
- Salicylic Acid Impurity 14 (CAS 607-85-2)
- Salicylic Acid EP Impurity B (CAS 636-46-4)
- Salicylic acid (potassium) (CAS 578-36-9)
- Salicylic Acid Methyl Ether-d3 (CAS 96739-36-5)
- Salicylic Acid Impurity 5 (CAS 26171-04-0)
- Salicylic Acid Impurity 25 (CAS 303-07-1)
- Salicylic acid-pentyl ester (CAS 2050-08-0)
- Salicylic Acid Impurity 17 (CAS 870806-51-2)
Recommended Standards
- Methoxamine Impurity 10 (CAS 1201-38-3)
- Esmolol Impurity 40 (CAS 61389-68-2)
- Methoxamine Impurity 9 (CAS 49710-99-8)
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- Landiolol Impurity 32 (CAS CATO-C4X-262132)
- Mesalazine Impurity 3 (CAS 98-73-7)
- Sodium aminosalicylate Impurity 4 (CAS 17540-51-1)
- 1-(5,6-Dimethylpyrazin-2-yl)ethanone (CAS 54300-10-6)
- 2-(4-Methoxyphenyl)-7-methylimidazo[1,2-a]pyridine-3-carbaldehyde (CAS 300708-62-7)
- (2-Methyl-1,4-dioxan-2-yl)methanamine hydrochloride (CAS 2138044-58-1)
- 5-Amino-2-methyl-2,3-dihydro-1H-inden-2-ol (CAS 913296-99-8)
- Cobalt(3+),tris(1,2-ethanediamine-κN1,κN2)-,chloride (1:3),(OC-6-11)- (CAS 13408-73-6)
- 3-Bromo-2-naphthonitrile (CAS 54245-34-0)
- D-Phe6-Tirzepatide (CAS CATO-CPTD788925)
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