Mesalazine Impurity 3 CAS 98-73-7

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.98-73-7
Molecular FormulaC11H14O2
Molecular Weight178.23 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Mesalazine Impurity 3 CAS 98-73-7 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 178.23 g/mol gives Mesalazine Impurity 3 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Mesalazine Impurity 3 (CAS 98-73-7) is a certified pharmaceutical impurity reference standard with the molecular formula C11H14O2 and a molecular weight of 178.23 g/mol.

Mesalazine Impurity 3 (C11H14O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

As a certified reference material (CRM), Mesalazine Impurity 3 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H14O2
Molecular Weight178.23 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity>95%
StorageStore at 2-8°C
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957

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