5-(Methylsulfonyl)isoindoline-1-carboxylic acid hydrochloride CAS 2101237-86-7
| CAS No. | 2101237-86-7 |
| Molecular Formula | C10H11NO4S |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
5-(Methylsulfonyl)isoindoline-1-carboxylic acid hydrochloride (CAS 2101237-86-7) is a high-purity analytical reference standard with the molecular formula C10H11NO4SHCl and a molecular weight of 277.72 g/mol.
The molecular framework of 5-(Methylsulfonyl)isoindoline-1-carboxylic acid hydrochloride (C10H11NO4SHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H11NO4S HCl |
| Molecular Weight | 277.72 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
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Recommended Standards
- Ethyl 1-ethyl-4-(4-fluorophenoxy)-3-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate (CAS 1092344-19-8)
- 2-(1H-1,2,4-Triazol-1-ylmethyl)cyclohexanone 313492-86-3 9922AD C9H13N3O (CAS 313492-86-3)
- 8-(3-(Difluoromethyl)phenyl)-4-methyl-2-methylene-6-oxohexahydro-[1,3,2]oxazaborolo[2,3-b][1,3,2]oxazaborol-4-ium-8-uide (CAS 1704703-80-9)
- N-Nitroso Cinacalcet Impurity 9 (CAS CATO-C4X-105980)
- 3,4,7,9-Tetramethyl-1,4-dihydro-[1,2,4]triazino[3,4-f]purine-6,8(7h,9h)-dione (CAS 382646-12-0)
- 6-Bromo-2-(2,2,2-trifluoroethyl)pyridazin-3(2h)-one (CAS 1824276-23-4)
- 3-Bromo-8-methoxyquinoline-6-carboxylic acid (CAS 2639205-50-6)
- (2-Chloro-3-(difluoromethyl)-6-methylpyridin-4-yl)methanol (CAS 1804664-58-1)
- (6-Chloro-3-methylpyrazin-2-yl)methanol (CAS 2639836-41-0)
- Pancreatic Polypeptide (rat) (CAS 90419-12-8)
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