1-(2,2,2-trifluoroacetyl)indoline-5-sulfonyl chloride CAS 210691-38-6

Purity 97%+In StockPharmaceutical Standards
CAS No.210691-38-6
Molecular FormulaC10H7ClF3NO3S
Molecular Weight313.68 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(2,2,2-trifluoroacetyl)indoline-5-sulfonyl chloride CAS 210691-38-6 chemical structure

Description

The molecular framework of 1-(2,2,2-trifluoroacetyl)indoline-5-sulfonyl chloride (C10H7ClF3NO3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

CATO supplies 1-(2,2,2-trifluoroacetyl)indoline-5-sulfonyl chloride (CAS 210691-38-6), a certified reference material (molecular formula C10H7ClF3NO3S, MW 313.68 g/mol) for analytical method development and quality control.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H7ClF3NO3S
Molecular Weight313.68 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2017
Halogen ContentF/Cl-containing
Nitrogen Atoms1
Sulfur Atoms1

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