3-Amino-6-chloro-2,2'-difluoro-6'-methoxy-[1,1'-biphenyl]-4-carboxylic acid CAS 2022975-62-6
| CAS No. | 2022975-62-6 |
| Molecular Formula | C14H10ClF2NO3 |
| Molecular Weight | 313.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 3-Amino-6-chloro-2,2'-difluoro-6'-methoxy-[1,1'-biphenyl]-4-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
3-Amino-6-chloro-2,2'-difluoro-6'-methoxy-[1,1'-biphenyl]-4-carboxylic acid (CAS 2022975-62-6), molecular formula C14H10ClF2NO3 and molecular weight 313.68 g/mol, is a CATO reference standard with documented purity and traceability.
3-Amino-6-chloro-2,2'-difluoro-6'-methoxy-[1,1'-biphenyl]-4-carboxylic acid (C14H10ClF2NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C14H10ClF2NO3 |
| Molecular Weight | 313.68 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Amino Standards
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Recommended Standards
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- Ethyl 5-amino-4-bromo-1-(sec-butyl)-1H-pyrazole-3-carboxylate (CAS 1427013-82-8)
- 2-(2-methylenecyclopropyl)ethanol (CAS 120477-28-3)
- 2-(Bicyclo[2.2.1]hept-5-en-2-yl)propan-2-ol (CAS 22497-08-1)
- 3-(4-Fluorobenzoyl)benzoic acid (CAS 159782-00-0)
- 3-oxobenzofuran-5-carboxylic acid (CAS 74815-32-0)
- 4-(Methoxymethyl)-1-methylquinolin-2(1H)-one (CAS 111724-88-0)
- 7-Methoxy-4-oxo-1,4-dihydro-1,5-naphthyridine-3-carboxylic acid (CAS 1352398-02-7)
- 5-Amino-1-benzyl-1H-1,2,3-triazole-4-carbaldehyde (CAS 49789-96-0)
- Halometasone Impurity 9 (CAS CATO-C4X-14469)
- Peptide Impurity 09 X TFA Salt (CAS CATO-CPTD788809)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com