Ethyl 4-(Trifluoromethyl)indole-3-carboxylate CAS 2110104-22-6
| CAS No. | 2110104-22-6 |
| Molecular Formula | C12H10F3NO2 |
| Molecular Weight | 257.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 4-(Trifluoromethyl)indole-3-carboxylate.
Ethyl 4-(Trifluoromethyl)indole-3-carboxylate (CAS 2110104-22-6) is a high-purity analytical reference standard with the molecular formula C12H10F3NO2 and a molecular weight of 257.21 g/mol.
Ethyl 4-(Trifluoromethyl)indole-3-carboxylate (C12H10F3NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Ethyl 4-(Trifluoromethyl)indole-3-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H10F3NO2 |
| Molecular Weight | 257.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- 1-((3-(Trifluoromethyl)phenoxy)methyl)-1h-pyrazol-4-amine (CAS 1006333-99-8)
- (4-Methyl-2-(4-(trifluoromethyl)phenyl)oxazol-5-yl)methanol (CAS 109544-12-9)
- Ethyl 2-(trifluoromethyl)-1H-indole-3-carboxylate (CAS 117643-82-0)
- 1-{3-[4-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl}ethan-1-amine (CAS 1199481-13-4)
- (1-(4-(Trifluoromethyl)benzyl)-1H-1,2,3-triazol-4-yl)methanol (CAS 1232164-02-1)
- ethyl 2-(trifluoromethyl)indolizine-1-carboxylate (CAS 1284226-15-8)
- 3-(2-(Trifluoromethyl)-1H-indol-3-yl)propanoic acid (CAS 1303974-41-5)
- 7-Trifluoromethyl-1H-indole-2-carboxylic acid ethyl ester (CAS 154422-28-3)
Recommended Standards
- Ethyl 4-(trifluoromethyl)-1H-indole-2-carboxylate (CAS 317-60-2)
- Ethyl 5-(trifluoromethyl)indole-2-carboxylate (CAS 201929-84-2)
- ethyl 2-(butyrylamino)-3,3,3-trifluoro-2-hydroxypropanoate (CAS 328270-25-3)
- Ethyl 6-(trifluoromethyl)-1H-indole-2-carboxylate (CAS 327-21-9)
- 2-Chloro-N-ethylethanamine (CAS 50871-01-7)
- 2-(2,4-Dichlorophenyl)-2-[4-(4-fluorobenzoyl)phenyl]acetonitrile (CAS 339115-06-9)
- 4-Bromo-N-(cyclopropylmethyl)-2-methylaniline (CAS 1156171-36-6)
- 2,2,2-trifluoroethyl N-(3-methoxypropyl)carbamate (CAS 1221724-58-8)
- 1-(6-Chloro-1-(2-methoxyethyl)-1H-benzo[d]imidazol-2-yl)ethan-1-one (CAS 1437434-01-9)
- [[2-(Diethylamino)-2-oxoethyl](4-methoxyphenyl)-amino]acetic acid (CAS 1142205-91-1)
- Methyl 5-(benzyloxy)pentanoate (CAS 31662-20-1)
- 2-(((1-Methoxypropan-2-yl)oxy)methyl)butane-1-sulfonyl chloride (CAS 1493491-07-8)
- Tert-butyl isopropyl(2-(methylamino)cyclohexyl)carbamate (CAS 1353955-83-5)
- Semaglutide impurity 199 (CAS CATO-C4X-2226199)
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