Avanafil Impurity 18 CAS 211230-35-2
| CAS No. | 211230-35-2 |
| Molecular Formula | C16H19N3O3S |
| Molecular Weight | 333.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Avanafil Impurity 18 (CAS 211230-35-2, C16H19N3O3S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C16H19N3O3S, Avanafil Impurity 18 contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 333.41 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Avanafil Impurity 18 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H19N3O3S |
| Molecular Weight | 333.41 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2017 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Avanafil Standards
- Avanafil Impurity 13 (CAS 330785-99-4)
- Avanafil Impurity 17 (CAS 330786-34-0)
- Avanafil Impurity 128 (CAS CATO-C4X-1118128)
- Avanafil Impurity 86 (CAS CATO-C4X-111886)
- Avanafil Impurity 85 (CAS CATO-C4X-111885)
- Avanafil Impurity 37 (CAS CATO-C4X-111837)
- Avanafil Impurity 42 (CAS CATO-C4X-111842)
- Avanafil Impurity 68 (CAS 2250243-09-3)
Recommended Standards
- (5E)-2-Mercapto-5-[(2-methyl-1H-indol-3-yl)-methylene]-3-phenyl-3,5-dihydro-4H-imidazol-4-one 681014-88-0 (CAS 681014-88-0)
- Rosuvastatin Impurity 165 (CAS CATO-C4X-1169165)
- N-Benzyl-3-(1H-pyrrol-1-yl)thieno[2,3-b]pyridine-2-carboxamide (CAS 951473-75-9)
- Enpromate (CAS 10087-89-5)
- Oseltamivir Impurity 25 (CAS 1132659-98-3)
- Difelikefalin Impurity 69 (CAS CATO-C4X-304169)
- Axitinib Impurity 73 (CAS CATO-C4X-107173)
- 2-((1R,3r)-3-(tert-butyl)cyclobutyl)ethan-1-ol (CAS 2231666-31-0)
- 39181-45-8 5-[(4-methylphenyl)methyl]-1,3,4-thiadiazol-2-amine Z1258519601 (CAS 39181-45-8)
- Boc-D-Ser-OH (CAS 6368-20-3)
- 3-(4-((Phenylamino)phenyl)imino)indolin-2-one (CAS 1374447-53-6)
- 4-Hydroxycyclohexyl acetate, mixture of diastereomers (CAS 58512-50-8)
- 2-Bromo-4-iodo-3-(trifluoromethyl)pyridine (CAS 1227496-78-7)
- Semaglutide impurity 55 (CAS CATO-C4X-222655)
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