Avanafil Impurity 85 CAS CATO-C4X-111885
| CAS No. | CATO-C4X-111885 |
| Molecular Formula | C15H16ClN3O3S |
| Molecular Weight | 353.82 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 353.82 g/mol gives Avanafil Impurity 85 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Avanafil Impurity 85 (CAS CATO-C4X-111885), a pharmacopoeial impurity reference standard (molecular formula C15H16ClN3O3S, MW 353.82 g/mol) used for the identification and quantification of trace impurities in APIs.
Avanafil Impurity 85 (C15H16ClN3O3S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Avanafil Impurity 85 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H16ClN3O3S |
| Molecular Weight | 353.82 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Avanafil Standards
- Avanafil Impurity 37 (CAS CATO-C4X-111837)
- Avanafil Impurity 68 (CAS 2250243-09-3)
- Avanafil Impurity 90 (CAS 2250242-49-8)
- Avanafil Impurity 86 (CAS CATO-C4X-111886)
- Avanafil Impurity 20 (CAS 2250242-42-1)
- Avanafil Impurity 17 (CAS 330786-34-0)
- Avanafil Impurity 33 (CAS CATO-C4X-111833)
- Avanafil Impurity 43 (CAS 330785-81-4)
Recommended Standards
- Clopidogrel Impurity 50 (CAS CATO-C4X-102950)
- 2-((4-Allyl-5-((4-chlorophenoxy)methyl)-4H-1,2,4-triazol-3-yl)thio)acetohydrazide (CAS 1306738-56-6)
- Clopidogrel Impurity 100 (CAS CATO-C4X-1029100)
- (E)-2-benzoyl-3-(1-((2-chlorothiazol-5-yl)methyl)-1H-pyrrol-2-yl)acrylonitrile (CAS 692732-76-6)
- Linagliptin Impurity 48 (CAS 853029-57-9)
- Atosiban Impurity 1 (CAS CATO-C4X-22931)
- Loratadine Methanone Impurity (CAS 119770-60-4)
- 6-(Trifluoromethyl)pyrimidine-4-carbaldehyde (CAS 933694-75-8)
- 2-Naphthalenesulfonic acid (CAS 120-18-3)
- 3,6-Dichloro-[1,2,4]triazolo[3,4-a]isoquinoline (CAS 7639-53-4)
- 5-(1-(4-Bromophenyl)-5-methyl-1H-1,2,3-triazol-4-yl)-3-(o-tolyl)-1,2,4-oxadiazole (CAS 899723-58-1)
- 5-(2,5-Dimethylphenoxy)furan-2-carbaldehyde (CAS 1291494-07-9)
- (R)-tert-Butyl 1-(3-benzyl-7-chloro-4-oxo-4H-chromen-2-yl)-2-methylpropylcarbamate (CAS 618430-24-3)
- Calcitonin C-Terminal Flanking Peptide (human) XTFA (CAS 85916-47-8（free base）)
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