5-Chloro-3,4-difluorobenzene-1,2-diamine CAS 211693-76-4

Purity 97%+In StockPharmaceutical Standards
CAS No.211693-76-4
Molecular FormulaC6H5ClF2N2
Molecular Weight178.57 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Chloro-3,4-difluorobenzene-1,2-diamine CAS 211693-76-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 178.57 g/mol gives 5-Chloro-3,4-difluorobenzene-1,2-diamine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

5-Chloro-3,4-difluorobenzene-1,2-diamine (CAS 211693-76-4) is a high-purity analytical reference standard with the molecular formula C6H5ClF2N2 and a molecular weight of 178.57 g/mol.

Owing to a nitrile group, fluorine/chlorine substitution, an aromatic ring system, 5-Chloro-3,4-difluorobenzene-1,2-diamine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 178.57 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC6H5ClF2N2
Molecular Weight178.57 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2017
Halogen ContentF/Cl-containing
Nitrogen Atoms2

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