Cinacalcet Impurity 22 CAS 21172-43-0
| CAS No. | 21172-43-0 |
| Molecular Formula | C11H13F3O3S |
| Molecular Weight | 282.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Cinacalcet Impurity 22 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Cinacalcet Impurity 22 (CAS 21172-43-0, C11H13F3O3S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Cinacalcet Impurity 22 (C11H13F3O3S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C11H13F3O3S |
| Molecular Weight | 282.28 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Cinacalcet Standards
- Cinacalcet Impurity 67 (CAS 3742-75-4)
- Cinacalcet Impurity N22 (CAS 2302907-04-4)
- Cinacalcet Impurity N86 (CAS 129254-76-8)
- Cinacalcet EP Impurity E (CAS 253337-60-9)
- Cinacalcet Impurity 95 (CAS CATO-C4X-105995)
- Cinacalcet Impurity 65 (CAS 1860814-97-6)
- Cinacalcet Impurity 93 (CAS CATO-C4X-105993)
- Cinacalcet Impurity 55 (CAS CATO-C4X-105955)
Recommended Standards
- 5930-73-4 Methyl thiopyrophosphate (((MeO)2PS)2S) (7CI) Thiodiphosphoric acid (((HO)2P(S))2S), tetramethyl ester (9CI) Thiodiphosphorothioic acid, O,O,O',O'-tetramethyl ester 4-01-00-01265 (Beilstein Handbook Reference) BRN 1712022 (CAS 5930-73-4)
- Flupentixol Impurity 29 (CAS CATO-C4X-189529)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com