2-Chloro-3-fluoro-4-(hydroxymethyl)phenylboronic acid CAS 2121512-25-0
| CAS No. | 2121512-25-0 |
| Molecular Formula | C7H7BClFO3 |
| Molecular Weight | 204.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 2-Chloro-3-fluoro-4-(hydroxymethyl)phenylboronic acid (CAS 2121512-25-0), a certified reference material (molecular formula C7H7BClFO3, MW 204.39 g/mol) for analytical method development and quality control.
2-Chloro-3-fluoro-4-(hydroxymethyl)phenylboronic acid (C7H7BClFO3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 2-Chloro-3-fluoro-4-(hydroxymethyl)phenylboronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H7BClFO3 |
| Molecular Weight | 204.39 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- (2-Chloro-6-fluoro-3-methoxyphenyl)boronic acid (CAS 1072945-77-7)
- (5-Chloro-2-fluoro-4-methoxyphenyl)boronic acid (CAS 1072952-18-1)
- 2-Chloro-4-fluoro-5-methoxyphenylboronic Acid (CAS 1256355-46-0)
- 3-Chloro-4-fluoro-5-methoxyphenylboronic acid (CAS 1379466-82-6)
- (4-Chloro-5-fluoro-2-methoxyphenyl)boronic acid (CAS 1443379-11-0)
- (3-Chloro-5-fluoro-4-methoxyphenyl)boronic acid (CAS 1451392-04-3)
- 4-Chloro-2-fluoro-3-hydroxymethylphenylboronic acid (CAS 1451393-58-0)
- (4-Chloro-2-fluoro-5-methoxyphenyl)boronic acid (CAS 153122-60-2)
Recommended Standards
- (6-Chloro-2-fluoro-3-methoxyphenyl)boronic acid (CAS 867333-04-8)
- 2-Chloro-4-fluoro-3-methoxyphenylboronic Acid (CAS 943831-11-6)
- (5-Chloro-4-fluoro-2-methoxyphenyl)boronic acid (CAS 949892-09-5)
- 2-Chloro-5-fluoro-3-methoxyphenylboronic acid (CAS 677741-96-7)
- ((4'-Nitro-[1,1'-biphenyl]-4-yl)sulfonyl)glycine (CAS 851176-29-9)
- (4Z)-3-tert-Butyl-1-phenyl-4-[(thiophen-3-yl)methylidene]-4,5-dihydro-1H-pyrazol-5-one (CAS 1025206-25-0)
- 2-(Chloromethyl)-6-(difluoromethyl)-4-iodopyridine-3-acetonitrile (CAS 1807102-67-5)
- 3-(Aminomethyl)-2-methylcyclopentan-1-ol (CAS 1561625-74-8)
- 4-Phenylthiophene-2-boronic acid (CAS 362612-68-8)
- 2-Chloro-N-cyclohexyl-N-methylbenzamide (CAS 300820-83-1)
- 4-[(2-Bromoacetyl)amino]-N-(1-phenylethyl)-benzamide (CAS 1138443-45-4)
- 3-methyl-4-(pyridin-3-yloxy)benzaldehyde (CAS 1250618-71-3)
- tert-Butyl-(3-(hydroxymethylene)-4-oxocyclohexyl)carbamate (CAS 911485-70-6)
- Semaglutide impurity 233 (CAS CATO-C4X-2226233)
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