2-Chloro-5-fluoro-3-methoxyphenylboronic acid CAS 677741-96-7
| CAS No. | 677741-96-7 |
| Molecular Formula | C7H7BClFO3 |
| Molecular Weight | 204.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 2-Chloro-5-fluoro-3-methoxyphenylboronic acid (CAS 677741-96-7), a certified reference material (molecular formula C7H7BClFO3, MW 204.39 g/mol) for analytical method development and quality control.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 2-Chloro-5-fluoro-3-methoxyphenylboronic acid is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 204.39 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 2-Chloro-5-fluoro-3-methoxyphenylboronic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H7BClFO3 |
| Molecular Weight | 204.39 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- (2-Chloro-6-fluoro-3-methoxyphenyl)boronic acid (CAS 1072945-77-7)
- (5-Chloro-2-fluoro-4-methoxyphenyl)boronic acid (CAS 1072952-18-1)
- 2-Chloro-4-fluoro-5-methoxyphenylboronic Acid (CAS 1256355-46-0)
- 3-Chloro-4-fluoro-5-methoxyphenylboronic acid (CAS 1379466-82-6)
- (4-Chloro-5-fluoro-2-methoxyphenyl)boronic acid (CAS 1443379-11-0)
- (3-Chloro-5-fluoro-4-methoxyphenyl)boronic acid (CAS 1451392-04-3)
- 4-Chloro-2-fluoro-3-hydroxymethylphenylboronic acid (CAS 1451393-58-0)
- (4-Chloro-2-fluoro-5-methoxyphenyl)boronic acid (CAS 153122-60-2)
Recommended Standards
- 2-Chloro-4-fluoro-3-methoxyphenylboronic Acid (CAS 943831-11-6)
- 3-Chloro-5-fluoro-2-methoxyphenylboronic acid (CAS 2121513-76-4)
- 2-Chloro-3-fluoro-4-(hydroxymethyl)phenylboronic acid (CAS 2121512-25-0)
- 3-Chloro-6-fluoro-2-methoxyphenylboronic acid (CAS 2121511-91-7)
- Hydroxybupropion-d8 (CAS 1309283-18-8)
- 4-Carboxyphenyl isothiocyanate (CAS 2131-62-6)
- Bis(2,4-dimethylphenyl)amine (CAS 19616-28-5)
- Lacidipine Impurity 28 (CAS CATO-C4X-167128)
- 6-Aminochromane-4-carboxylic acid (CAS 1342853-32-0)
- 4-Chloro-3-isopropyl-1H-indazole (CAS 1415740-51-0)
- H-Asp-Ala-His-Lys-OH (CAS 111543-77-2)
- CL 316243 Disodium Salt (CAS 138908-40-4)
- α-D-Glucosamine pentaacetate (CAS 7784-54-5)
- Semaglutide Impurity 157 (x TFA Salt) (CAS CATO-C4X-2226157)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com