Rizatriptan Impurity 1 CAS 212248-62-9
| CAS No. | 212248-62-9 |
| Molecular Formula | C9H11N5 |
| Molecular Weight | 189.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Rizatriptan Impurity 1 (CAS 212248-62-9) is a high-purity analytical reference standard with the molecular formula C9H11N5 and a molecular weight of 189.22 g/mol.
The molecular framework of Rizatriptan Impurity 1 (C9H11N5) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Rizatriptan Impurity 1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H11N5 |
| Molecular Weight | 189.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2017 |
| Nitrogen Atoms | 5 |
Related Rizatriptan Standards
- Rizatriptan Impurity 10 (CAS 63516-03-0)
- Rizatriptan Impurity 13 (CAS 91192-27-7)
- Rizatriptan Impurity 12 (CAS 700-37-8)
- Rizatriptan Impurity 15 (CAS 114094-45-0)
- Rizatriptan Impurity 24 (CAS 119192-11-9)
- Rizatriptan Impurity 12 (CAS 119192-09-5)
- Rizatriptan Impurity 11 (CAS 119192-10-8)
- Rizatriptan Impurity 15 (CAS 6085-94-5)
Recommended Standards
- N-Methyl-1-[3-(1H-tetrazol-5-yl)phenyl]methanamine (CAS 915920-43-3)
- Triethylenethiophosphoramide (CAS 52-24-4)
- N-benzyl-1-methyl-1H-tetrazol-5-amine (CAS 66907-74-2)
- 2-Phenylthiazole-5-carbaldehyde (CAS 1011-40-1)
- (S)-1-Benzyl 2-methyl 4-propyl-1H-pyrrole-1,2(2H,5H)-dicarboxylate (CAS 1798902-94-9)
- 8-Allyloxy-n2-(dimethylaminomethylidene)-2'-deoxyguanosine (CAS 869354-73-4)
- tert-Butyl (3R)-3-(1-hydroxy-1-methyl-ethyl)piperazine-1-carboxylate (CAS 502546-05-6)
- 4-Bromo-1-chloro-2-(2,2-difluoroethoxy)benzene (CAS 1343731-27-0)
- 3-Methyl-4-(piperazin-1-yl)-1,2,5-oxadiazole hydrochloride (CAS 843608-98-0)
- 4-(2-Chlorothieno[2,3-d]pyrimidin-4-yl)morpholine (CAS 63894-67-7)
- 4-Allyl-5-(o-tolyl)-4H-1,2,4-triazole-3-thiol (CAS 423741-70-2)
- Omeprazole Impurity 50 (CAS CATO-C4X-125550)
- 5-Chloro-2-(methylthio)benzaldehyde (CAS 91827-45-1)
- Semaglutide Impurity 75 (CAS CATO-C4X-2226175)
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