Linezolid Impurity 18 CAS 212325-40-1
| CAS No. | 212325-40-1 |
| Molecular Formula | C12H15FN2O3 |
| Molecular Weight | 254.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 254.26 g/mol gives Linezolid Impurity 18 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Linezolid Impurity 18 (CAS 212325-40-1), a pharmacopoeial impurity reference standard (molecular formula C12H15FN2O3, MW 254.26 g/mol) used for the identification and quantification of trace impurities in APIs.
Linezolid Impurity 18 (C12H15FN2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Linezolid Impurity 18 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H15FN2O3 |
| Molecular Weight | 254.26 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2017 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Linezolid Standards
- Linezolid Impurity 19 (CAS CATO-C4X-153519)
- Linezolid Impurity 34 (CAS CATO-C4X-107334)
- Linezolid Impurity 114 (CAS CATO-C4X-1073114)
- Linezolid Impurity 36 (CAS 3459-92-5)
- Linezolid impurity 28 (CAS 79669-87-7)
- Linezolid Impurity 6 (CAS 565176-83-2)
- Linezolid Impurity 48 (CAS 1532560-87-4)
- Linezolid Impurity 60 (CAS 333753-72-3)
Recommended Standards
- Edaravone Impurity 13 (CAS 76407-98-2)
- Piroxicam EP Impurity C (CAS 24683-25-8)
- 7-amino-5-hydroxy-2-phenyl-4H-chromen-4-one-8-d (CAS CATO-C3D-262404)
- N-Acetyl Zonisamide (CAS 68936-43-6)
- Salbutamol impurity 166 (CAS 2919946-71-5)
- Ledipasvir Impurity 23 (CAS CATO-C4X-331323)
- Baclofen impurity 24 (CAS 28311-34-4（Free Base）)
- N1-(2-Fluorobenzyl)-N1-methylethane-1,2-diamine (CAS 1096873-48-1)
- 3-(2-(Trifluoromethyl)phenyl)cyclohexanone (CAS 1391136-54-1)
- 2-amino-1,2,3,4-tetrahydroisoquinoline-1,3-dione (CAS 22177-46-4)
- 5-Amino-3-hydroxy-2-methylquinoline-4-carboxylic acid (CAS 61358-59-6)
- 1-(difluoromethyl)cyclobutane-1-carbaldehyde (CAS 1781544-23-7)
- 2-(4-Methoxy-3-(4-methoxyphenyl)-6-oxopyridazin-1(6H)-yl)propanoic acid (CAS 1437432-59-1)
- Semaglutide Impurity 123 (CAS 71997-93-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com