4-Ethoxy-2,3-difluorophenylboronic Acid CAS 212386-71-5
| CAS No. | 212386-71-5 |
| Molecular Formula | C8H9BF2O3 |
| Molecular Weight | 201.96 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Ethoxy-2,3-difluorophenylboronic Acid (CAS 212386-71-5), molecular formula C8H9BF2O3 and molecular weight 201.96 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C8H9BF2O3, 4-Ethoxy-2,3-difluorophenylboronic Acid contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 201.96 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Ethoxy-2,3-difluorophenylboronic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H9BF2O3 |
| Molecular Weight | 201.96 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2017 |
| Halogen Content | F-containing |
Related Ethoxy Standards
- (6-Ethoxy-2,3-difluorophenyl)boronic acid (CAS 1309980-95-7)
- (4-Ethoxy-2,6-difluorophenyl)boronic acid (CAS 1310403-94-1)
- (4-Ethoxy-2,5-difluorophenyl)boronic acid (CAS 1452575-83-5)
- (2-Ethoxy-4,5-difluorophenyl)boronic acid (CAS 870778-87-3)
- (5-Ethoxy-2,4-difluorophenyl)boronic acid (CAS 900175-12-4)
- 3-Ethoxy-2,4-difluorophenylboronic acid (CAS 2096341-72-7)
- 4-Ethoxy-3,5-difluorophenylboronic acid (CAS 2096333-93-4)
- 4-Ethoxy-3,5-difluorobenzoic acid (CAS 1017779-19-9)
Recommended Standards
- 3,5-Difluoro-4-methoxy-2-methylphenylboronic acid (CAS 2096338-65-5)
- (2,2-Bis(methoxycarbonyl)cyclopropyl)boronic acid (CAS 2225151-98-2)
- 3,4-Dichloro-2,5,6-trifluoropyridine (CAS 52026-99-0)
- (2-(Pyrazin-2-yl)pyrimidin-5-yl)boronic acid (CAS 2225178-68-5)
- 4-chloro-3H-imidazo[4,5-c]pyridine-6-carbonitrile (CAS 1352896-31-1)
- Diethyl [(2,4-dinitrophenyl)amino]malonate (CAS 36309-52-1)
- Methyl 2-chloro-3-iodobenzoate (CAS 620621-51-4)
- n-((5-Methyl-1,2,4-oxadiazol-3-yl)methyl)-N-(pyrrolidin-3-yl)acetamide (CAS 1421601-33-3)
- 2-Pentynoic Acid Methyl Ester (CAS 24342-04-9)
- 3-Chloro-4-(pyrrolidin-1-yl)benzaldehyde (CAS 886500-61-4)
- Phenyl (4,6-dimethylpyrimidin-2-yl)carbamate (CAS 89819-24-9)
- 4-Amino-2-((2-amino-2-oxoethyl)thio)thiazole-5-carboxamide (CAS 13807-05-1)
- N-(3,5-Dichlorobenzyl)-3-(2-methoxyethoxy)aniline (CAS 1040686-73-4)
- endo-Arg30-Semaglutide (CAS CATO-C4X-2226281)
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