(2-Ethoxy-4,5-difluorophenyl)boronic acid CAS 870778-87-3
| CAS No. | 870778-87-3 |
| Molecular Formula | C8H9BF2O3 |
| Molecular Weight | 201.96 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
(2-Ethoxy-4,5-difluorophenyl)boronic acid (CAS 870778-87-3) is a high-purity analytical reference standard with the molecular formula C8H9BF2O3 and a molecular weight of 201.96 g/mol.
(2-Ethoxy-4,5-difluorophenyl)boronic acid (C8H9BF2O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H9BF2O3 |
| Molecular Weight | 201.96 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
Related Ethoxy Standards
- (6-Ethoxy-2,3-difluorophenyl)boronic acid (CAS 1309980-95-7)
- (4-Ethoxy-2,6-difluorophenyl)boronic acid (CAS 1310403-94-1)
- (4-Ethoxy-2,5-difluorophenyl)boronic acid (CAS 1452575-83-5)
- (5-Ethoxy-2,4-difluorophenyl)boronic acid (CAS 900175-12-4)
- 3-Ethoxy-2,4-difluorophenylboronic acid (CAS 2096341-72-7)
- 4-Ethoxy-2,3-difluorophenylboronic Acid (CAS 212386-71-5)
- 4-Ethoxy-3,5-difluorophenylboronic acid (CAS 2096333-93-4)
- 4-Ethoxy-3,5-difluorobenzoic acid (CAS 1017779-19-9)
Recommended Standards
- (3-(Difluoromethyl)-4-methoxyphenyl)boronic acid (CAS 1704065-70-2)
- (3-(2,2-Difluoroethoxy)phenyl)boronic acid (CAS 958452-33-0)
- (4-(2,2-Difluoroethoxy)phenyl)boronic acid (CAS 958453-65-1)
- 3,4-Difluoro-2-ethoxyphenylboronic acid (CAS 1451391-69-7)
- 5-Nitro-2,4,6-triaminopyrimidine (CAS 24867-36-5)
- 4-(Bromomethyl)-2-(difluoromethyl)-3,6-dimethoxypyridine (CAS 1805325-00-1)
- 1-(3,4-Dimethylphenyl)-3-(2-methoxyphenyl)propan-1-one (CAS 898770-06-4)
- 2-(piperazin-2-yl)ethan-1-ol (CAS 3388-79-2)
- 2-(5-Chloro-7-methoxybenzo[d]isoxazol-3-yl)acetic acid (CAS 1708288-36-1)
- 2-[(2E)-2-{2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-2-methylhydrazin-1-ylidene}ethyl]-9,10-dihydroanthracene-9,10-dione (CAS 338961-95-8)
- 8-Ethyl-4-(3-fluorobenzoyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326808-69-8)
- (1-(3,4-Dichlorophenyl)-1H-1,2,3-triazol-4-yl)methyl benzoate (CAS 338419-31-1)
- Tris(2,2,2-trifluoroacetoxy)aluminum (CAS 127649-67-6)
- Liraglutide(3-31)TFA Salt (CAS CATO-C4X-19921)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com