Levofloxacin Impurity 36 CAS 2130840-88-7
| CAS No. | 2130840-88-7 |
| Molecular Formula | C20H23FN4O6 |
| Molecular Weight | 434.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Levofloxacin Impurity 36.
CATO supplies Levofloxacin Impurity 36 (CAS 2130840-88-7), a pharmacopoeial impurity reference standard (molecular formula C20H23FN4O6, MW 434.42 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Levofloxacin Impurity 36 (C20H23FN4O6) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 434.42 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H23FN4O6 |
| Molecular Weight | 434.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Levofloxacin Standards
- Levofloxacin Impurity 34 (CAS CATO-C4X-137134)
- Levofloxacin Impurity 32 (CAS 1329833-82-0)
- Levofloxacin Impurity 58 (CAS CATO-C4X-137158)
- Levofloxacin impurity 65 (CAS CATO-C4X-137165)
- Levofloxacin Impurity 19 (CAS 2206135-16-0)
- Levofloxacin Impurity 42 (CAS 1330277-19-4)
- Levofloxacin Impurity 41 (CAS CATO-C4X-137141)
- Levofloxacin Impurity 99 (CAS 902172-11-6)
Recommended Standards
- Cefamandole EP Impurity E (CAS 87932-78-3)
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- Lemborexant Impurity 105 (CAS CATO-C4X-3042105)
- Cytarabine Impurity 24 (CAS CATO-C4X-200524)
- Indometacin Impurity 62 (CAS CATO-C4X-147062)
- Perospirone Impurity 43 (CAS CATO-C4X-245843)
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- 4-Butoxy-2,6-difluorobenzenesulfonyl chloride (CAS 1706431-01-7)
- 3-Iodobenzofuran (CAS 905752-25-2)
- Propyl piperidine-2-carboxylate hydrochloride (CAS 1218743-55-5)
- Ibrutinib Impurity 51 (CAS CATO-C4X-106451)
- propyl 2-(1H-indol-3-yl)acetate (CAS 2122-68-1)
- Semaglutide impurity 89 (CAS CATO-C4X-222689)
Why CATO?
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