Ibrutinib Impurity 51 CAS CATO-C4X-106451
| CAS No. | CATO-C4X-106451 |
| Molecular Formula | C14H15BO3 |
| Molecular Weight | 242.08 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ibrutinib Impurity 51 is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Ibrutinib Impurity 51 (CAS CATO-C4X-106451) is a certified pharmaceutical impurity reference standard with the molecular formula C14H15BO3 and a molecular weight of 242.08 g/mol.
The molecular framework of Ibrutinib Impurity 51 (C14H15BO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Ibrutinib Impurity 51 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H15BO3 |
| Molecular Weight | 242.08 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Ibrutinib Standards
- Ibrutinib Impurity 181 (CAS 79888-54-3)
- Ibrutinib Impurity 81 (CAS 143667-36-1)
- Ibrutinib Impurity 79 (CAS 21218-94-0)
- Ibrutinib Impurity 193 (CAS 60034-89-1)
- Ibrutinib Impurity 151 (CAS CATO-C4X-1064151)
- Ibrutinib Impurity 143 (CAS CATO-C4X-1064143)
- Ibrutinib Impurity 154 (CAS CATO-C4X-1064154)
- Ibrutinib Impurity 155 (CAS CATO-C4X-1064155)
Recommended Standards
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- 5-(Methoxymethyl)-2,3-dihydro-1,3,4-oxadiazol-2-one (CAS 1711-90-6)
- 2-Ethoxy-1H-benzo[d]imidazole-6-carbonitrile (CAS 952511-49-8)
- 2,6-Bis(2,2,2-trifluoroethoxy)-3-bromobenzonitrile (CAS 175204-13-4)
- 1,3,5-Tris[4-(dihydroxyboryl)phenyl]benzene (CAS 900795-73-5)
- D-Ser32-Tirzepatide (CAS CATO-CPTD788677)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com