Almonertinib Hydrochloride CAS 2134096-03-8
| CAS No. | 2134096-03-8 |
| Molecular Formula | C30H35N7O2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Almonertinib Hydrochloride.
Almonertinib Hydrochloride (CAS 2134096-03-8), molecular formula C30H35N7O2HCl and molecular weight 562.12 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Almonertinib Hydrochloride (C30H35N7O2HCl) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C30H35N7O2 HCl |
| Molecular Weight | 562.12 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >98% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 7 |
Related Almonertinib Standards
Recommended Standards
- Butyl 2-(morpholin-2-yl)acetate (CAS 1522650-38-9)
- 4-methoxycyclohexane-1-sulfonyl chloride (CAS 1565980-23-5)
- 1-(tert-Butyl)-3-iodo-5-methylbenzene (CAS 111220-30-5)
- 6-Amino-N-cyclohexyl-3-methylbenzo[4,5]imidazo[2,1-b]thiazole-2-carboxamide (CAS 299901-57-8)
- N-(3-Fluorophenyl)-2-nitro-4-(piperidin-1-ylmethyl)aniline (CAS 509093-96-3)
- 4,6-Dichloro-2-(4-fluorophenyl)pyrimidine (CAS 83217-30-5)
- 3-Methyl-4-(trifluoromethoxy)phenol (CAS 1261793-16-1)
- 5-Chloro-1-(4-fluoro-3-methylphenyl)-1-oxopentane (CAS 898761-06-3)
- (R)-1-(2-chlorophenyl)-2-methoxyethan-1-amine (CAS 1269967-60-3)
- Fibrinogen-Binding Peptide (CAS 137235-80-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com