Vortioxetine Impurity 28 CAS 2135577-60-3
| CAS No. | 2135577-60-3 |
| Molecular Formula | C24H32N2O5S |
| Molecular Weight | 460.59 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Vortioxetine Impurity 28 (CAS 2135577-60-3), a pharmacopoeial impurity reference standard (molecular formula C24H32N2O5S, MW 460.59 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Vortioxetine Impurity 28 (C24H32N2O5S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H32N2O5S |
| Molecular Weight | 460.59 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Vortioxetine Standards
- Vortioxetine Impurity 14 (CAS 1240670-85-2)
- Vortioxetine Impurity 58 (CAS CATO-C4X-105658)
- Vortioxetine Impurity 50 (CAS CATO-C4X-105650)
- Vortioxetine Impurity 40 (CAS CATO-C4X-105640)
- Vortioxetine Impurity 53 (CAS CATO-C4X-105653)
- Vortioxetine Impurity 21 (CAS CATO-C4X-105621)
- Vortioxetine Impurity 26 (CAS 2243045-82-9)
- Vortioxetine Impurity 28 (CAS CATO-C4X-105628)
Recommended Standards
- N,N-Dibenzyl-N'-[(benzylcarbamothioyl)amino]butanediamide (CAS 331461-08-6)
- Nor Acetildenafil-D8 (CAS 1185117-07-0)
- 10-(Triphenylphosphoranylidene)decyl acetate (CAS 88634-88-2)
- 4-[2-(4-Hydroxyphenyl)ethyl]phenyl 4-(nonyloxy)benzoate (CAS 133763-67-4)
- Norepinephrine Impurity 66 HCl (CAS 62-22-6)
- Enoxacin Impurity 3 (CAS 79286-73-0)
- Acetaminophen Impurity 41 (CAS CATO-C4X-121141)
- 4-Iodo-N,N-dimethyl-1H-imidazole-1-sulfonamide (CAS 135773-25-0)
- 2,4-Difluoro-6-(trifluoromethyl)benzonitrile (CAS 1805057-04-8)
- ((2R,3R)-4-(anthracen-9-yl)-3-(tert-butyl)-2,3-dihydrobenzo[d][1,3]oxaphosphol-2-yl)di-tert-butylphosphine oxide (CAS 2545293-88-5)
- 4-Hydroxybenzothiazole-2-carboxylic acid (CAS 1261783-68-9)
- 2-(2,4-dimethylphenyl)cyclobutan-1-amine hydrochloride (CAS 1955541-11-3)
- 9-(4-Biphenylyl)-9’-phenyl-9H,9’H-3,3’-bicarbazole (CAS 1454567-05-5)
- Peptide 439 (CAS CATO-CPTD788439)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com