(4,4-Difluorotetrahydrofuran-2-yl)methanamine CAS 2137857-47-5
| CAS No. | 2137857-47-5 |
| Molecular Formula | C5H9F2NO |
| Molecular Weight | 137.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
(4,4-Difluorotetrahydrofuran-2-yl)methanamine (CAS 2137857-47-5), molecular formula C5H9F2NO and molecular weight 137.13 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (4,4-Difluorotetrahydrofuran-2-yl)methanamine (C5H9F2NO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), (4,4-Difluorotetrahydrofuran-2-yl)methanamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H9F2NO |
| Molecular Weight | 137.13 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluorotetrahydrofuran Standards
- (3,3-Difluorotetrahydrofuran-2-yl)methanol (CAS 2718966-09-5)
- (4,4-difluorotetrahydrofuran-2-yl)methanol (CAS 2288623-47-0)
- 4,4-difluorotetrahydrofuran-3-ol (CAS 1782515-61-0)
- 4,4-Difluorotetrahydrofuran-3-amine (CAS 1785430-57-0)
- (S)-3,3-difluorotetrahydrofuran-2-carboxylic acid (CAS 1108713-62-7)
- 4,4-Difluorotetrahydrofuran-3-carboxylic acid (CAS 1510016-98-4)
- (R)-4,4-difluorotetrahydrofuran-2-carboxylic acid (CAS 2165345-34-4)
- (S)-4,4-difluorotetrahydrofuran-2-carboxylic acid (CAS 2165729-43-9)
Recommended Standards
- (4,4-Difluoropyrrolidin-3-yl)methanol (CAS 763060-99-7)
- (R)-3,3-Difluoropiperidin-4-ol (CAS 2199320-91-5)
- (3S,5S)-5-(difluoromethyl)pyrrolidin-3-ol (CAS 2306254-95-3)
- (R)-4,4-difluoropiperidin-3-ol (CAS 2306254-81-7)
- 4-Chloro-N-(1-(2,6-dichlorobenzyl)-2-oxo-1,2-dihydropyridin-3-yl)butanamide (CAS 338784-91-1)
- 4-Amino-N-(1H-benzo[d]imidazol-2-yl)benzenesulfonamide (CAS 52715-11-4)
- 2,3-Dihydro-9,10-dihydroxy-1,4-anthracenedione (CAS 17648-03-2)
- Phenanthrene-1,2-dione (CAS 573-12-6)
- N1-Ethylmalonohydrazide (CAS 25457-53-8)
- 3,6-Dichloro-2-(difluoromethoxy)benzyl chloride (CAS 1806328-40-4)
- Nebivolol Impurity 75 (CAS CATO-C4X-196875)
- (2-Fluoro-4-((2,2,2-trifluoroethoxy)methyl)phenyl)boronic acid (CAS 1704064-28-7)
- [5-(Benzyloxy)-2-methoxyphenyl]boronic acid (CAS 2051586-00-4)
- D-Ile27-Tirzepatide (CAS CATO-CPTD788907)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com