(4-Bromo-1-methyl-1H-pyrazol-3-yl)methanesulfonyl chloride CAS 2138010-82-7
| CAS No. | 2138010-82-7 |
| Molecular Formula | C5H6BrClN2O2S |
| Molecular Weight | 273.54 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
(4-Bromo-1-methyl-1H-pyrazol-3-yl)methanesulfonyl chloride (CAS 2138010-82-7) is a high-purity analytical reference standard with the molecular formula C5H6BrClN2O2S and a molecular weight of 273.54 g/mol.
The molecular framework of (4-Bromo-1-methyl-1H-pyrazol-3-yl)methanesulfonyl chloride (C5H6BrClN2O2S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H6BrClN2O2S |
| Molecular Weight | 273.54 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Bromo Standards
- 4-Bromo-1,5-dimethyl-1h-pyrazole-3-sulfonyl chloride (CAS 1538239-71-2)
- (4-Bromo-1-methyl-1H-pyrazol-5-yl)methanesulfonyl chloride (CAS 1708436-36-5)
- 5-bromo-1,2-dimethyl-1H-imidazole-4-sulfonyl chloride (CAS 1803604-65-0)
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- 3-Bromo-7-chlorothieno[3,2-b]pyridine-6-carbonitrile (CAS 798574-82-0)
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Recommended Standards
- 2',3,5'-Trichloro-[1,1'-biphenyl]-2-ol (CAS 67651-38-1)
- 2,4,4'-Trichlorobiphenyl ether (CAS 59039-21-3)
- Dodecylmagnesium bromide solution (CAS 15890-72-9)
- 4-Hydroxy-2',4',6'-trichlorobiphenyl (CAS 14962-28-8)
- 313526-24-8 IBR2 (CAS 313526-24-8)
- (2E)-3-(4-Chlorophenyl)-1-[2-(4-chlorophenyl)-4-methyl-1,3-thiazol-5-yl]prop-2-en-1-one (CAS 95793-51-4)
- BT2F-2Th8Br (CAS 1283598-36-6)
- 7'-Bromo-1,3,3',4'-tetrahydro-1'H-spiro[indene-2,2'-naphthalen]-1'-one (CAS 1272758-07-2)
- 104778-58-7 1-Benzyl-3-(chloromethyl)piperidine DTXSID30547599 (CAS 104778-58-7)
- 6-Chloro-3-methoxy-2-nitrophenylboronic acid (CAS 2377609-70-4)
- 2-(Aminomethyl)-6-(difluoromethyl)-5-(trifluoromethoxy)pyridine-3-sulfonyl chloride (CAS 1806759-69-2)
- 7-Chloro-N-(2,5-dimethylphenyl)quinazolin-4-amine (CAS 477856-44-3)
- 1-Methyl-3-phenyl-1H-pyrazole (CAS 3463-26-1)
- Liraglutide Impurity 15 TFA Salt (CAS CATO-C4X-199215)
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