2-(Piperazin-1-yl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile dihydrochloride CAS 2138062-24-3
| CAS No. | 2138062-24-3 |
| Molecular Formula | C14H18N4 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(Piperazin-1-yl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile dihydrochloride.
CATO supplies 2-(Piperazin-1-yl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile dihydrochloride (CAS 2138062-24-3), a certified reference material (molecular formula C14H18N4HCl, MW 278.78 g/mol) for analytical method development and quality control.
The molecular framework of 2-(Piperazin-1-yl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile dihydrochloride (C14H18N4HCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H18N4 2*HCl |
| Molecular Weight | 278.78 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Piperazin Standards
- 2-(3-(Piperazin-1-yl)propyl)isoindoline-1,3-dione (CAS 1000547-80-7)
- (4-Methyl-piperazin-1-yl)-(S)-pyrrolidin-2-yl-methanone (CAS 100158-68-7)
- (6-(Piperazin-1-yl)pyridin-3-yl)boronic acid (CAS 1003043-67-1)
- (2-(Piperazin-1-yl)pyridin-4-yl)boronic acid (CAS 1003043-70-6)
- N-(4-(Piperazin-1-ylsulfonyl)phenyl)acetamide (CAS 100318-71-6)
- Piperazin-1-yl(m-tolyl)methanone hydrochloride (CAS 100940-01-0)
- 2-(Piperazin-1-yl)phenol (CAS 1011-17-2)
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Recommended Standards
- (1R,3S)-3-(ethoxycarbonyl)cyclopentane-1-carboxylic acid (CAS 62959-17-5)
- (4-Cyclopropoxy-2-ethylpyridin-3-yl)methanamine (CAS 1243310-63-5)
- (Z)-[(4-Fluorophenyl)[2-(4-methylphenyl)cyclopropyl]methylidene]amino 4-methylbenzoate (CAS 338749-02-3)
- 1-(3,5-Dimethylphenyl)-3-phenylpropan-1-one (CAS 898764-33-5)
- 5-Ethyl-2-methyl-1H-indole-3-acetic Acid (CAS 299166-69-1)
- 3-(5-(Trifluoromethyl)-1,3,4-oxadiazol-2-yl)aniline (CAS 1197229-53-0)
- 6-Ethyl-5-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile (CAS 113124-05-3)
- (8-Amino-3,4-dihydro-2H-1,4-ethanothieno[2,3-b][1,5]naphthyridin-7-yl)(4-chlorophenyl)methanone (CAS 899371-27-8)
- 4-Cyano-6-(difluoromethyl)-2-methoxypyridine-3-methanol (CAS 1806950-38-8)
- Liraglutide(8-31)TFA Salt (CAS CATO-C4X-19922)
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