2-Iodo-3-methyl-6-(trifluoromethyl)-3H-imidazo[4,5-b]pyridine CAS 2138063-20-2
| CAS No. | 2138063-20-2 |
| Molecular Formula | C8H5F3IN3 |
| Molecular Weight | 327.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 2-Iodo-3-methyl-6-(trifluoromethyl)-3H-imidazo[4,5-b]pyridine (C8H5F3IN3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/iodine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 327.05 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
2-Iodo-3-methyl-6-(trifluoromethyl)-3H-imidazo[4,5-b]pyridine (CAS 2138063-20-2), molecular formula C8H5F3IN3 and molecular weight 327.05 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H5F3IN3 |
| Molecular Weight | 327.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
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- 5-(Aminomethyl)-3-(difluoromethyl)-6-(trifluoromethoxy)pyridin-2-amine (CAS 1804608-75-0)
- 2-(((Furan-2-ylmethyl)thio)methyl)piperidine (CAS 1249781-38-1)
- (1S,2R)-4-Bromocyclohexa-3,5-diene-1,2-diol (CAS 154333-43-4)
- 2-Amino-6-ethylbenzoic Acid (CAS 66232-56-2)
- N-(1-(3-methoxypropyl)-2-oxo-1,2-dihydrobenzo[cd]indol-6-yl)-1-(thiophen-2-ylsulfonyl)piperidine-2-carboxamide (CAS 2417772-39-3)
- Des-Ile17-Tirzepatide (CAS CATO-CPTD788956)
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