7-Hydroxy-2-oxo-2H-chromene-4-carboxylic acid CAS 21392-45-0
| CAS No. | 21392-45-0 |
| Molecular Formula | C10H6O5 |
| Molecular Weight | 206.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
7-Hydroxy-2-oxo-2H-chromene-4-carboxylic acid (CAS 21392-45-0), molecular formula C10H6O5 and molecular weight 206.15 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system, 7-Hydroxy-2-oxo-2H-chromene-4-carboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 206.15 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 7-Hydroxy-2-oxo-2H-chromene-4-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H6O5 |
| Molecular Weight | 206.15 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
Related Hydroxy Standards
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Recommended Standards
- 6-Nitroisoquinoline-1,3(2H,4H)-dione (CAS 611187-02-1)
- 7-Hydroxy-2-oxo-2H-chromene-6-carboxylic acid (CAS 833-52-3)
- 6,8-Difluoro-4-hydroxyquinoline-3-carbonitrile (CAS 61338-23-6)
- 7-Hydroxy-4-oxo-4h-chromene-2-carboxylic acid (CAS 30113-83-8)
- Amyloid β-Protein (40-1) trifluoroacetate salt (CAS 144409-99-4)
- Hexahydro-1-(phenylmethyl)-1H-azepin-3-ol (CAS 148473-84-1)
- 3-Amino-5-(4-(tert-butyl)phenyl)thiophene-2-carboxamide (CAS 306935-13-7)
- 2-Amino-N-(1-benzylpyrrolidin-3-yl)-N-cyclopropylacetamide (CAS 1353946-84-5)
- 4-Ethoxybenzofuran-2-carboxamide (CAS 199287-56-4)
- 5-tert-Butyl-1,2,3-trimethylbenzene (CAS 98-23-7)
- 4-Methyl-2-oxo-1,2-dihydroquinoline-7-carboxylic acid (CAS 124281-65-8)
- 2-(tert-butoxy)pyridin-3-ol (CAS 1243404-19-4)
- Ethyl 1-(2-morpholinoethyl)-1h-pyrazole-4-carboxylate (CAS 874196-88-0)
- Neuropeptide W-23 (rat) (CAS 383415-89-2)
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