Vancomycin EP Impurity A HCl CAS 213997-73-0
| CAS No. | 213997-73-0 |
| Molecular Formula | C65H73Cl2N9O24 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Vancomycin EP Impurity A HCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Vancomycin EP Impurity A HCl (CAS 213997-73-0), a pharmacopoeial impurity reference standard (molecular formula C65H73Cl2N9O24HCl, MW 1471.70 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Vancomycin EP Impurity A HCl (C65H73Cl2N9O24HCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 32.0, corresponding to approximately 32 ring(s) or double-bond equivalent(s). With a molecular weight of 1471.70 g/mol, it falls into the high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C65H73Cl2N9O24 HCl |
| Molecular Weight | 1471.70 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 32.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2018 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 9 |
Related Vancomycin Standards
- Vancomycin EP Impurity D (CAS 101485-50-1)
- Vancomycin Hexapeptide (CAS 115236-65-2)
- 126985-51-1 MM 47761 Vancomycin, 22-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-D-arabino-hexopyranosyl)-2'-O-de(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-19-dechloro-2'-O-(6-deoxy-alpha-D-talopyranosyl)- MM-47761 (CAS 126985-51-1)
- Vancomycin (CAS 1404-90-6)
- Vancomycin Hydrochloride (CAS 1404-93-9)
- Vancomycin EP Impurity F (CAS 2415254-43-0)
- Vancomycin EP Impurity J (CAS 2416251-24-4)
- Vancomycin impurity 17 (CAS 250273-66-6)
Recommended Standards
- Zolpidem Acid Impurity 2 (CAS 189005-44-5)
- Flurbiprofen Impurity 98 (CAS CATO-C4X-144498)
- Pefloxacin EP Impurity H (CAS 106847-40-9)
- 2,2-Dimethyl-1-(5-methyl-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indol-1-yl)propan-1-one (CAS 2376879-95-5)
- 1'-Ethyl-1'H-spiro[piperidine-4,2'-quinazolin]-4'(3'H)-one (CAS 1325304-82-2)
- (2S,3S,4R,5R,6S)-2,3,4,5,6,7-hexahydroxyheptanal (CAS 4305-74-2)
- (2-Methoxy-1,4-phenylene)dimethanamine (CAS 119402-72-1)
- 6-Bromo-2-fluoronicotinaldehyde (CAS 1227588-87-5)
- 1H-indole-2,3-dione, 5-bromo-4-iodo- (CAS 63037-66-1)
- (10-31)Semaglutide (CAS CATO-C4X-2226283)
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