Vancomycin EP Impurity D CAS 101485-50-1
| CAS No. | 101485-50-1 |
| Molecular Formula | C59H62Cl2N8O22 |
| Molecular Weight | 1306.07 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Vancomycin EP Impurity D (CAS 101485-50-1), a pharmacopoeial impurity reference standard (molecular formula C59H62Cl2N8O22, MW 1306.07 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Vancomycin EP Impurity D (C59H62Cl2N8O22) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Vancomycin EP Impurity D under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C59H62Cl2N8O22 |
| Molecular Weight | 1306.07 g/mol |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 32.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 8 |
Related Vancomycin Standards
- Vancomycin Hexapeptide (CAS 115236-65-2)
- Vancomycin Didechloro Impurity (CAS 98510-30-6)
- Vancomycin EP Impurity H (CAS 357396-41-9)
- Vancomycin EP Impurity G (CAS CATO-C4X-17758)
- Vancomycin impurity 24 (CAS CATO-C4X-177524)
- Vancomycin EP Impurity A (CAS 91700-98-0(Free Base))
- Vancomycin impurity 23 (CAS CATO-C4X-177523)
- Vancomycin impurity 25 (CAS CATO-C4X-177525)
Recommended Standards
- 4,4',4'',4''',4'''',4'''''-(9,10-Dihydro-9,10-[1,2]benzenoanthracene-2,3,6,7,14,15-hexayl)hexakis(2,6-diisopropylaniline) (CAS 2564798-15-6)
- (Des-Gly10,D-Arg6,Pro-NHEt9)-LHRH II (chicken) (CAS 145940-57-4)
- 4',4''',4''''',4'''''''-(Ethene-1,1,2,2-tetrayl)tetrakis(N,N-diphenyl-[1,1'-biphenyl]-4-amine) (CAS 1416786-56-5)
- (Tyr9)-Cholecystokinin Octapeptide (sulfated) (H-9770.0005) (CAS 96607-61-3)
- Sunitinib Impurity 80 (CAS CATO-C4X-133380)
- Cefpodoxime Proxetil Impurity 40 (CAS 911000-43-6)
- Parecoxib Impurity 34 (CAS CATO-C4X-159134)
- Pregabalin Impurity 54 (CAS 616-42-2)
- 1-MEthyl-4-[(6-piperidin-4-ylpyridin-3-yl)carbonyl]piperazine dihydrochloride (CAS 1858256-82-2)
- 5-Amino-4,4-dimethyl-3,4-dihydroisoquinolin-1(2h)-one (CAS 2168632-35-5)
- (S)-1-(tert-Butoxycarbonyl)-2,3-dihydro-1H-pyrrole-2-carboxylic acid (CAS 90104-21-5)
- 6-Bromo-8-methoxy-2H-chromene-3-carboxylic acid methyl ester (CAS 885271-18-1)
- 3-(1h-Pyrrol-1-yl)-3-(thiophen-3-yl)propanoic acid (CAS 866019-33-2)
- Des-Pro36-37-Tirzepatide (CAS CATO-CPTD788938)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com