Cytarabine EP Impurity G CAS 2140-61-6
| CAS No. | 2140-61-6 |
| Molecular Formula | C10H15N3O5 |
| Molecular Weight | 257.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Cytarabine EP Impurity G is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Cytarabine EP Impurity G (CAS 2140-61-6, C10H15N3O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, Cytarabine EP Impurity G is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 257.24 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H15N3O5 |
| Molecular Weight | 257.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 3 |
Related Cytarabine Standards
- Cytarabine EP Impurity I (CAS 6829-31-8)
- Cytarabine Impurity 18 (Cytidine N3-Oxide) (CAS 3310-47-2)
- Cytarabine Impurity 8 (CAS 58461-29-3)
- Cytarabine Impurity N3 (CAS 30902-36-4)
- Cytarabine Impurity 11 (CAS CATO-C4X-200511)
- Cytarabine Impurity 17 (CAS 69321-95-5)
- Cytarabine Impurity 10 (CAS CATO-C4X-200510)
- Cytarabine Impurity 7 (CAS 32659-31-7)
Recommended Standards
- 5-(Hydroxymethyl)-2’-deoxycytidine (CAS 7226-77-9)
- Bumetanide Impurity 69 (CAS CATO-C4X-198669)
- Yellow no. 3 (CAS 56932-45-7)
- Deferasirox EP Impurity A (CAS 1972-71-0)
- Dexmedetomidine Impurity 65 (CAS CATO-C4X-123065)
- Ibuprofen impurity 131 (CAS CATO-C4X-1082131)
- Tegoprazan Impurity 123 (CAS CATO-C4X-2297123)
- 20451-53-0 Phenyl vinyl sulphoxide EINECS 243-831-6 (CAS 20451-53-0)
- N-(5-Amino-2-methoxyphenyl)-2-[2,4-di(tert-butyl)-phenoxy]acetamide (CAS 1020056-14-7)
- (R)-2-(6-Benzhydrylpyridin-2-yl)-4-benzyl-4,5-dihydrooxazole (CAS 2417528-14-2)
- Boc-D-β-HomoSec(pMeBzl)-OH (CAS 2044709-91-1)
- Methyl 5-amino-6-bromo-3-methylpyrazine-2-carboxylate (CAS 1823921-17-0)
- N-(2-Methoxyethyl)-N-(6-oxo-1,6-dihydropyridazin-3-yl)acetamide (CAS 88259-91-0)
- Neuropeptide W-23 (human) (CAS 383415-79-0)
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