2'-O-Methyladenosine CAS 2140-79-6

Purity >95%In StockPharmaceutical Standards
CAS No.2140-79-6
Molecular FormulaC11H15N5O4
Molecular Weight281.27 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2'-O-Methyladenosine CAS 2140-79-6 chemical structure

Description

2'-O-Methyladenosine (CAS 2140-79-6) is a high-purity analytical reference standard with the molecular formula C11H15N5O4 and a molecular weight of 281.27 g/mol.

Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, 2'-O-Methyladenosine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 281.27 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC11H15N5O4
Molecular Weight281.27 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity>95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Nitrogen Atoms5

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