Epinastine Impurity N7 CAS 21535-43-3
| CAS No. | 21535-43-3 |
| Molecular Formula | C15H14ClNO |
| Molecular Weight | 259.73 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Epinastine Impurity N7 (CAS 21535-43-3), a pharmacopoeial impurity reference standard (molecular formula C15H14ClNO, MW 259.73 g/mol) used for the identification and quantification of trace impurities in APIs.
Epinastine Impurity N7 (C15H14ClNO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H14ClNO |
| Molecular Weight | 259.73 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Epinastine Standards
- Epinastine Impurity 12 (CAS 745761-19-7)
- Epinastine Impurity 24 (CAS 1110929-19-5)
- Epinastine Impurity 58 (CAS CATO-C4X-184058)
- Epinastine Impurity 45 (CAS CATO-C4X-184045)
- Epinastine Impurity 27 (CAS CATO-C4X-184027)
- Epinastine Impurity 57 (CAS CATO-C4X-184057)
- Epinastine Impurity 41 (CAS CATO-C4X-184041)
- Epinastine Impurity 9 (CAS 141342-71-4)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com