Epinastine Impurity N5 CAS 21535-44-4
| CAS No. | 21535-44-4 |
| Molecular Formula | C15H12ClN |
| Molecular Weight | 241.72 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Epinastine Impurity N5 (CAS 21535-44-4) is a certified pharmaceutical impurity reference standard with the molecular formula C15H12ClN and a molecular weight of 241.72 g/mol.
Structurally, Epinastine Impurity N5 (C15H12ClN) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 241.72 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H12ClN |
| Molecular Weight | 241.72 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Epinastine Standards
- Epinastine Impurity 52 (CAS 150399-28-3)
- Epinastine Impurity 36 (CAS CATO-C4X-184036)
- Epinastine Impurity 26 (CAS CATO-C4X-184026)
- Epinastine Impurity 43 (CAS 41218-85-3)
- Epinastine EP Impurity A (CAS 706753-75-5)
- Epinastine (CAS 80012-43-7)
- Epinastine Impurity 57 (CAS CATO-C4X-184057)
- Epinastine Impurity 58 (CAS CATO-C4X-184058)
Recommended Standards
- Ribociclib Impurity 22 (CAS CATO-C4X-310022)
- N-[(2-CHloro-4-fluorophenyl)methyl]cyclohexanamine (CAS 1021113-98-3)
- N1-methyl-n1-(2-methyl-4,5,6,7-tetrahydro-2h-indazol-3-yl)-2-chloroacetamide (CAS 246020-77-9)
- 4-(Chloromethyl)-1-(3-fluorobenzyl)piperidine (CAS 1341899-73-7)
- Atosiban Impurity 58 (CAS CATO-C4X-229358)
- Palonosetron Impurity 9 (CAS 2446343-19-5)
- Afatinib Impurity 91 (CAS 2512206-82-3)
- Levocarnitine Impurity 17 (CAS 90866-33-4)
- 2-(S-(fluoromethyl)-N-tosylsulfinimidoyl)phenolate (CAS 1097193-08-2)
- 3-(3,5-Dimethyl-1h-pyrazol-1-yl)butan-1-amine (CAS 1006323-23-4)
- Methyl 6-(4-ethoxyphenyl)-2-methylnicotinate (CAS 1447960-36-2)
- 1-Fluoro-2,5-dimethyl-4-nitrobenzene (CAS 1736-88-5)
- 2-tert-butyl-4-(piperazin-1-ylmethyl)-1,3-thiazole (CAS 1094661-15-0)
- Cholecystokinin, CCK Tetrapeptide (30-33) (CAS 35144-91-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com