8-(Iodomethyl)quinoline CAS 215606-70-5
| CAS No. | 215606-70-5 |
| Molecular Formula | C10H8IN |
| Molecular Weight | 269.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 8-(Iodomethyl)quinoline.
CATO supplies 8-(Iodomethyl)quinoline (CAS 215606-70-5), a certified reference material (molecular formula C10H8IN, MW 269.08 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, iodine substitution, 8-(Iodomethyl)quinoline is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 269.08 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 8-(Iodomethyl)quinoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8IN |
| Molecular Weight | 269.08 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2018 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Related Iodomethyl Standards
- 2-(3-(Iodomethyl)pyrrolidin-1-yl)acetic acid (CAS 1353978-46-7)
- 2-(2-(Iodomethyl)pyrrolidin-1-yl)acetic acid (CAS 1353979-98-2)
- 2-(Iodomethyl)quinoline (CAS 170289-38-0)
- 4-(Iodomethyl)quinoline (CAS 500350-44-7)
- 6-(Iodomethyl)quinoline (CAS 99361-10-1)
- trans-3-(iodomethyl)-1,1,4-trimethyl-silolane (CAS 144930-15-4)
- ethyl 3-(iodomethyl)cyclobutanecarboxylate (CAS 2730888-05-6)
- [3-ethyl-5-(iodomethyl)oxolan-3-yl]methanol (CAS 2031261-16-0)
Recommended Standards
- 7-Iodonaphthalen-2-amine (CAS 845464-04-2)
- 8-Iodo-2-methylquinoline (CAS 254106-45-1)
- 7-Iodo-8-methylquinoline (CAS 2453297-11-3)
- 8-Iodo-naphthalen-1-ylamine (CAS 52753-62-5)
- 1-(3,4-Difluorophenyl)pentan-1-one (CAS 1094374-82-9)
- 5-fluoroimidazo[1,2-a]pyridine-2-carbaldehyde (CAS 878197-67-2)
- 9,9-bis(4-aminophenyl)fluorene (CAS 15499-84-0)
- 1-(2,4-Difluorophenyl)-n-ethylpropan-2-amine (CAS 1249226-76-3)
- (2e)-3-[4-(carbamoylmethoxy)phenyl]prop-2-enoic acid (CAS 873811-55-3)
- 2,4,6-trimethyl-1,3-benzothiazole (CAS 80689-37-8)
- Methyl 4,6-dimethylmorpholine-2-carboxylate (CAS 2089257-07-6)
- 2-(4-Chlorophenyl)-4-methylpyridine (CAS 23182-19-6)
- 4-Methoxy-2-morpholinoaniline (CAS 144187-56-4)
- endo-Arg30-Semaglutide (CAS CATO-C4X-2226281)
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