8-Iodo-2-methylquinoline CAS 254106-45-1
| CAS No. | 254106-45-1 |
| Molecular Formula | C10H8IN |
| Molecular Weight | 269.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 8-Iodo-2-methylquinoline (CAS 254106-45-1), a certified reference material (molecular formula C10H8IN, MW 269.08 g/mol) for analytical method development and quality control.
The molecular framework of 8-Iodo-2-methylquinoline (C10H8IN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures 8-Iodo-2-methylquinoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H8IN |
| Molecular Weight | 269.08 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Related Iodo Standards
- 3-IODO-5-METHYLCINNAMONITRILE (CAS 1018450-07-1)
- 6-Iodo-2-methylquinoline (CAS 1128-62-7)
- 3-Iodo-2-methylquinoline (CAS 1207875-09-9)
- 8-Iodo-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine (CAS 1228666-17-8)
- 6-Iodo-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine (CAS 1246088-42-5)
- 2-Iodo-isonicotinic acid methyl ester (CAS 134579-47-8)
- 3-iodo-8-methylquinoline (CAS 1424245-96-4)
- 3-Iodo-6-methylquinoline (CAS 1424246-00-3)
Recommended Standards
- 8-(Iodomethyl)quinoline (CAS 215606-70-5)
- 8-Iodo-naphthalen-1-ylamine (CAS 52753-62-5)
- 7-Iodonaphthalen-2-amine (CAS 845464-04-2)
- ethyl 2-(3-bromo-1-bicyclo[1.1.1]pentanyl)-2,2-difluoro-acetate (CAS 2374230-65-4)
- 6-Bromo-8-chloroisoquinoline (CAS 1824270-14-5)
- 8-Methyl-2-(trifluoromethyl)quinoline (CAS 1860-46-4)
- 4-(Trifluoromethyl)-1,4,5,6-tetrahydropyrimidine (CAS 1306606-70-1)
- 6-(Difluoromethyl)-3-(hydroxymethyl)-2-methylisonicotinonitrile (CAS 1807149-63-8)
- 5674-02-2 Isobutylmagnesium chloride, 2M in THF MFCD00000471 Chloro(2-methylpropyl)magnesium (CAS 5674-02-2)
- (2E)-4,4,4-Trifluoro-2-butenoic acid (CAS 406-94-0)
- 2-(tert-Butyl)-3H-imidazo[4,5-b]pyridine (CAS 21714-58-9)
- 2-(4-(Difluoromethyl)-3-hydroxy-5-iodopyridin-2-yl)acetic acid (CAS 1807007-78-8)
- 1,3-Diphenyl-1h-pyrazol-4-amine (CAS 216854-39-6)
- Influenza PR8 Hemagglutinin Peptide (110-119) (H-6312.0005) (CAS 132031-50-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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