Tert-butyl (3R,5R)-3-hydroxy-5-(trifluoromethyl)piperidine-1-carboxylate CAS 2165480-63-5
| CAS No. | 2165480-63-5 |
| Molecular Formula | C11H18F3NO3 |
| Molecular Weight | 269.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Tert-butyl (3R,5R)-3-hydroxy-5-(trifluoromethyl)piperidine-1-carboxylate (C11H18F3NO3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies Tert-butyl (3R,5R)-3-hydroxy-5-(trifluoromethyl)piperidine-1-carboxylate (CAS 2165480-63-5), a certified reference material (molecular formula C11H18F3NO3, MW 269.26 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Tert-butyl (3R,5R)-3-hydroxy-5-(trifluoromethyl)piperidine-1-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H18F3NO3 |
| Molecular Weight | 269.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- tert-Butyl (2S,4S)-2-(hydroxymethyl)-4-(trifluoromethyl)pyrrolidine-1-carboxylate (CAS 470482-40-7)
- Tert-butyl (3S,5S)-3-hydroxy-5-(trifluoromethyl)piperidine-1-carboxylate (CAS 2165897-55-0)
- tert-Butyl (2S,4R)-4-hydroxy-2-(trifluoromethyl)piperidine-1-carboxylate (CAS 2613300-14-2)
- Tert-butyl (R)-2-((R)-2,2,2-trifluoro-1-hydroxyethyl)pyrrolidine-1-carboxylate (CAS 2306245-56-5)
- 1-(5-bromo-1H-indol-3-yl)ethan-1-ol (CAS 1553992-62-3)
- N1-(4-(trifluoromethyl)phenyl)propane-1,3-diamine (CAS 190127-70-9)
- 3-[(Methoxymethoxy)methyl]phenylboronic acid (CAS 2096342-14-0)
- 1,2-Di-p-tolylethene (CAS 1588-49-4)
- 4-(1-Methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamido)butanoic acid (CAS 956323-69-6)
- 2-(3-Chloro-4-fluorophenoxy)-N-(prop-2-yn-1-yl)acetamide (CAS 923243-39-4)
- Benzofuran-2-ylmethanethiol (CAS 54778-45-9)
- 5-Fluoro-3-phenylpyridin-2-amine (CAS 1214331-56-2)
- 7-Amino-4-(4-fluorobenzyl)-2-isopropyl-2H-benzo[b][1,4]oxazin-3(4H)-one (CAS 1082178-29-7)
- TRAF6 Control Peptide trifluoroacetate salt (CAS 852690-80-3)
Why CATO?
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