(R)-1-(tert-butoxycarbonyl)-4,4-difluoropiperidine-2-carboxylic acid CAS 2166008-44-0
| CAS No. | 2166008-44-0 |
| Molecular Formula | C11H17F2NO4 |
| Molecular Weight | 265.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, (R)-1-(tert-butoxycarbonyl)-4,4-difluoropiperidine-2-carboxylic acid is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 265.25 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
(R)-1-(tert-butoxycarbonyl)-4,4-difluoropiperidine-2-carboxylic acid (CAS 2166008-44-0), molecular formula C11H17F2NO4 and molecular weight 265.25 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (R)-1-(tert-butoxycarbonyl)-4,4-difluoropiperidine-2-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H17F2NO4 |
| Molecular Weight | 265.25 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- (R)-1-(tert-butoxycarbonyl)-3,3-difluoropiperidine-2-carboxylic acid (CAS 2165687-14-7)
- (S)-1-(tert-butoxycarbonyl)-3,3-difluoropiperidine-2-carboxylic acid (CAS 2165735-31-7)
- (E)-N'-((5-nitrofuran-2-yl)methylene)thiophene-2-carbohydrazide (CAS 328585-87-1)
- (S)-1-(tert-Butoxycarbonyl)-4,4-difluoropiperidine-3-carboxylic acid (CAS 2301077-33-6)
- 1-(3-Bromo-4-methoxybenzyl)cyclopropan-1-amine (CAS 1260854-95-2)
- lithium salt;2-pyridazin-3-ylacetic acid (CAS 1845687-62-8)
- tert-Butyl 3-cyano-4-fluorobenzylcarbamate (CAS 368426-87-3)
- 1-Methyl-4-[2-(2-piperidinyl)ethyl]piperazinedihydrochloride (CAS 1220021-54-4)
- 2-(Difluoromethoxy)-5-mercaptobenzo[d]oxazole (CAS 1803740-98-8)
- 3-(Pyrrolidin-1-yl)pyrazin-2-amine (CAS 912773-12-7)
- Ethyl 3-fluoro-8-hydroxy-2-methylquinoline-6-carboxylate (CAS 2721375-24-0)
- 4-(5-Nitrobenzimidazol-2-yl)aniline Hydrochloride (CAS 1385694-71-2)
- 2-Methylanthra[2,1,9-def:6,5,10-d'e'f']diisoquinoline-1,3,8,10(2H,9H)-tetraone (CAS 67892-42-6)
- Semaglutide impurity 23 (CAS CATO-C4X-222623)
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