Tert-butyl (S)-3-(difluoromethyl)piperazine-1-carboxylate CAS 2166007-82-3
| CAS No. | 2166007-82-3 |
| Molecular Formula | C10H18F2N2O2 |
| Molecular Weight | 236.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, Tert-butyl (S)-3-(difluoromethyl)piperazine-1-carboxylate is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 236.26 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Tert-butyl (S)-3-(difluoromethyl)piperazine-1-carboxylate (CAS 2166007-82-3), molecular formula C10H18F2N2O2 and molecular weight 236.26 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H18F2N2O2 |
| Molecular Weight | 236.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- Tert-butyl (S)-2-(difluoromethyl)piperazine-1-carboxylate (CAS 2165338-39-4)
- Tert-butyl (S)-4-(aminomethyl)-3,3-difluoropyrrolidine-1-carboxylate (CAS 2380445-82-7)
- tert-Butyl (S)-(4,4-difluoropiperidin-3-yl)carbamate (CAS 2089321-16-2)
- tert-Butyl (s)-4-amino-3,3-difluoropiperidine-1-carboxylate (CAS 2415515-29-4)
- Ethyl 4-bromo-5-methoxy-1H-indole-2-carboxylate (CAS 30933-69-8)
- 6-Chloro-4-isopropoxy-1H-pyrazolo[3,4-d]pyrimidine (CAS 637768-52-6)
- 4-Bromo-1-methoxy-2-(methylsulfinyl)benzene (CAS 1865164-90-4)
- Benzyl 3,9-diazaspiro[5.6]Dodecane-9-carboxylate (CAS 2387599-42-8)
- 3,6-Dicyclopropyl-1-(2-fluorophenyl)-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1018164-66-3)
- Propane-1,3-diyl dioctanoate (CAS 56519-71-2)
- N,N-dimethylbutyramide (CAS 760-79-2)
- 1-Bromo-4-(cyclohexanesulfonyl)benzene (CAS 861113-45-3)
- Vilanterol Impurity 83 (CAS CATO-C4X-193583)
- Liraglutide(10-22)TFA Salt (CAS CATO-C4X-199211)
Why CATO?
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