(3S)-1-[(tert-butoxy)carbonyl]-5,5-difluoropiperidine-3-carboxylicacid CAS 2166022-52-0
| CAS No. | 2166022-52-0 |
| Molecular Formula | C11H17F2NO4 |
| Molecular Weight | 265.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, (3S)-1-[(tert-butoxy)carbonyl]-5,5-difluoropiperidine-3-carboxylicacid is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 265.25 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
(3S)-1-[(tert-butoxy)carbonyl]-5,5-difluoropiperidine-3-carboxylicacid (CAS 2166022-52-0) is a high-purity analytical reference standard with the molecular formula C11H17F2NO4 and a molecular weight of 265.25 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (3S)-1-[(tert-butoxy)carbonyl]-5,5-difluoropiperidine-3-carboxylicacid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H17F2NO4 |
| Molecular Weight | 265.25 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- (3R,4R)-1-(tert-Butoxycarbonyl)-4-(difluoromethyl)pyrrolidine-3-carboxylic acid (CAS 1993278-98-0)
- (4r)-1-Tert-butoxycarbonyl-3,3-difluoro-piperidine-4-carboxylicacid (CAS 2382269-75-0)
- (3r)-1-[(tert-butoxy)carbonyl]-5,5-difluoropiperidine-3-carboxylicacid (CAS 2166031-07-6)
- (4s)-1-Tert-butoxycarbonyl-3,3-difluoro-piperidine-4-carboxylicacid (CAS 2197504-56-4)
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