2-Bromo-4-(difluoromethyl)-1-(trifluoromethoxy)benzene CAS 2166881-48-5
| CAS No. | 2166881-48-5 |
| Molecular Formula | C8H4BrF5O |
| Molecular Weight | 291.01 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Bromo-4-(difluoromethyl)-1-(trifluoromethoxy)benzene is closely related to a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-Bromo-4-(difluoromethyl)-1-(trifluoromethoxy)benzene (CAS 2166881-48-5), a certified reference material (molecular formula C8H4BrF5O, MW 291.01 g/mol) for analytical method development and quality control.
Owing to a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system, 2-Bromo-4-(difluoromethyl)-1-(trifluoromethoxy)benzene is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 291.01 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H4BrF5O |
| Molecular Weight | 291.01 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 2-Bromo-3,5-dinitrobenzoic acid (CAS 116529-60-3)
- 1-Bromo-2-(difluoromethoxy)-4-(trifluoromethyl)benzene (CAS 1417567-20-4)
- 1-Bromo-3-(difluoromethoxy)-5-(trifluoromethyl)benzene (CAS 1417567-27-1)
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- 2-Bromo-4-(difluoromethoxy)benzotrifluoride (CAS 1805502-40-2)
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Recommended Standards
- 2-Bromo-1-(difluoromethoxy)-4-(trifluoromethyl)benzene (CAS 954236-03-4)
- 3,6-Difluoro-2-(Trifluoromethoxy)benzyl bromide (CAS 2244076-54-6)
- 2,6-Difluoro-4-(Trifluoromethoxy)benzyl bromide (CAS 2244082-19-5)
- 4-Bromo-1-(difluoromethoxy)-2-(trifluoromethyl)benzene (CAS 954236-13-6)
- (E)-1-Bromo-2-(2-nitrovinyl)benzene (CAS 155988-33-3)
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- 3-[(3-Bromobenzyl)oxy]benzaldehyde (CAS 137489-76-0)
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