4-Bromo-1-(difluoromethoxy)-2-(trifluoromethyl)benzene CAS 954236-13-6
| CAS No. | 954236-13-6 |
| Molecular Formula | C8H4BrF5O |
| Molecular Weight | 291.01 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system, 4-Bromo-1-(difluoromethoxy)-2-(trifluoromethyl)benzene is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 291.01 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 4-Bromo-1-(difluoromethoxy)-2-(trifluoromethyl)benzene (CAS 954236-13-6), a certified reference material (molecular formula C8H4BrF5O, MW 291.01 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H4BrF5O |
| Molecular Weight | 291.01 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 2-Bromo-3,5-dinitrobenzoic acid (CAS 116529-60-3)
- 1-Bromo-2-(difluoromethoxy)-4-(trifluoromethyl)benzene (CAS 1417567-20-4)
- 1-Bromo-3-(difluoromethoxy)-5-(trifluoromethyl)benzene (CAS 1417567-27-1)
- 5-Bromo-1,3-difluoro-2-(2,2,2-trifluoroethoxy)benzene (CAS 145767-78-8)
- 2-Bromo-4-(difluoromethoxy)benzotrifluoride (CAS 1805502-40-2)
- 3-Bromo-2-(difluoromethoxy)benzotrifluoride (CAS 1805502-49-1)
- 2-Bromo-5-(difluoromethoxy)benzotrifluoride (CAS 1805524-34-8)
- 2-Bromo-6-(difluoromethoxy)benzotrifluoride (CAS 1805583-96-3)
Recommended Standards
- 3,6-Difluoro-2-(Trifluoromethoxy)benzyl bromide (CAS 2244076-54-6)
- 4-Bromo-2,6-dinitrobenzoic Acid (CAS 95192-56-6)
- 2-Bromo-4-(difluoromethyl)-1-(trifluoromethoxy)benzene (CAS 2166881-48-5)
- 4-Bromo-3,5-dinitrobenzoic acid (CAS 577-52-6)
- Benzyl 4-(2-oxoimidazolidin-1-yl)piperidine-1-carboxylate (CAS 72349-01-0)
- 6-(4-methylphenyl)-4,5-dihydropyridazin-3(2H)-one (CAS 1079-72-7)
- Methyl benzo[d]thiazole-2-carboxylate (CAS 87802-07-1)
- (E)-2-(2-((3-methylthiophen-2-yl)methylene)hydrazinyl)-3-(trifluoromethyl)quinoxaline (CAS 338962-30-4)
- 5-(1H-pyrazol-1-yl)thiophene-2-carboxylic acid (CAS 74990-40-2)
- 1,7-Dibromoisoquinolin-3-amine (CAS 925672-86-2)
- 1-(3,3,3-Trifluoropropyl)-1h-pyrazole-4-carboxylic acid (CAS 1342402-27-0)
- (R)-tert-Butyl 3-{[(4-fluorophenyl)methyl]amino}piperidine-1-carboxylate (CAS 1349699-72-4)
- 4-Chloro-3-(5-methyl-3-((4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-amino)benzo[e][1,2,4]triazin-7-yl)phenyl benzoate (CAS 867331-82-6)
- Tirzepatide Impurity 38 (CAS CATO-C4X-324038)
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