3-(difluoromethyl)cyclobutane-1-sulfonyl chloride CAS 2167400-97-5
| CAS No. | 2167400-97-5 |
| Molecular Formula | C5H7ClF2O2S |
| Molecular Weight | 204.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(difluoromethyl)cyclobutane-1-sulfonyl chloride is closely related to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-(difluoromethyl)cyclobutane-1-sulfonyl chloride (CAS 2167400-97-5), molecular formula C5H7ClF2O2S and molecular weight 204.62 g/mol, is a CATO reference standard with documented purity and traceability.
3-(difluoromethyl)cyclobutane-1-sulfonyl chloride (C5H7ClF2O2S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-(difluoromethyl)cyclobutane-1-sulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H7ClF2O2S |
| Molecular Weight | 204.62 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 1 |
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Recommended Standards
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- 4-Methyl-4-phenylpentan-2-yl acetate (CAS 68083-58-9)
- 4-Bromo-6-fluoro-2-(trifluoromethyl)quinoline (CAS 31009-33-3)
- 2-Bromo-1-(4-methyl-2-(pyrazin-2-yl)thiazol-5-yl)ethan-1-one (CAS 423768-43-8)
- 4-Bromo-3-(sec-butoxymethyl)-1-(difluoromethyl)-1H-pyrazole (CAS 1856074-90-2)
- (R)-6,6a,7,8,9,10-Hexahydro-5H-pyrido[1,2-a]quinoxaline (CAS 1414960-54-5)
- Methyl 2-phenylcyclopropanecarboxylate (CAS 20030-70-0)
- 1-(4-Methoxy-2-methylphenyl)-3-[3-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]urea (CAS 2096997-05-4)
- Insulin B (22-25) (CAS 34367-73-2)
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