5-fluoropyrrolo[2,1-f][1,2,4]triazin-4-amine CAS 2167769-26-6

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-fluoropyrrolo[2,1-f][1,2,4]triazin-4-amine.

5-fluoropyrrolo[2,1-f][1,2,4]triazin-4-amine (CAS 2167769-26-6) is a high-purity analytical reference standard with the molecular formula C6H13FN4 and a molecular weight of 160.19 g/mol.

The molecular framework of 5-fluoropyrrolo[2,1-f][1,2,4]triazin-4-amine (C6H13FN4) is characterized by a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 5-fluoropyrrolo[2,1-f][1,2,4]triazin-4-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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