4-Amino-3,3-difluoropyrrolidin-2-one CAS 2168867-16-9
| CAS No. | 2168867-16-9 |
| Molecular Formula | C4H6F2N2O |
| Molecular Weight | 136.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 136.10 g/mol gives 4-Amino-3,3-difluoropyrrolidin-2-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 4-Amino-3,3-difluoropyrrolidin-2-one (CAS 2168867-16-9), a certified reference material (molecular formula C4H6F2N2O, MW 136.10 g/mol) for analytical method development and quality control.
4-Amino-3,3-difluoropyrrolidin-2-one (C4H6F2N2O) contains an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Amino-3,3-difluoropyrrolidin-2-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C4H6F2N2O |
| Molecular Weight | 136.10 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Amino Standards
- 4-Amino-6-oxo-1,6-dihydropyrimidine-5-carbonitrile (CAS 109831-83-6)
- 4-Amino-2-hydroxypyrimidine-5-carbonitrile (CAS 16462-28-5)
- (E)-2-(3-Amino-5-oxofuran-2(5H)-ylidene)acetonitrile (CAS 19459-07-5)
- 2-Amino-4-oxo-1,4-dihydropyrimidine-5-carbonitrile (CAS 27058-50-0)
- 5-Amino-2-oxo-2,3-dihydropyrimidine-4-carbonitrile (CAS 371203-93-9)
- 6-Amino-2-hydroxypyrimidine-4-carbonitrile (CAS 548466-39-3)
- 3-Amino-4,4,4-trifluoro-2-butenenitrile (CAS 33561-24-9)
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Recommended Standards
- 3,3-difluorooxan-4-one (CAS 2169339-81-3)
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- cis-2-(difluoromethyl)cyclopropanecarboxylic acid (CAS 2278284-80-1)
- 3-Methyl-1H-1,2,4-triazole-5-sulfonamide (CAS 29982-54-5)
- 1-Methyl-4-oxo-4,7-dihydro-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid (CAS 54738-83-9)
- 5-Methyl-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)pyrazolo[1,5-a]pyrimidine (CAS 942589-64-2)
- 3-(((Benzyloxy)carbonyl)amino)-4-methylpentanoic acid (CAS 109446-56-2)
- 2-(Benzylamino)-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde (CAS 303024-38-6)
- 2-(4-Benzylmorpholin-3-yl)acetic acid (CAS 111949-91-8)
- Sodium 4-(2-(3-(1,1-dimethyl-3-(4-sulfonatobutyl)-1,3-dihydro-2H-benzo[e]indol-2-ylidene)prop-1-en-1-yl)-1,1-dimethyl-1H-benzo[e]indol-3-ium-3-yl)butane-1-sulfonate (CAS 1438644-82-6)
- Methyl2-(4-aminophenyl)acetatehydrochloride (CAS 83528-16-9)
- 4,6-Difluorosalicylic acid (CAS 189283-54-3)
- [5-31]-Semaglutide (CAS CATO-C4X-2226263)
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