Vonoprazan Impurity 43 CAS 2169271-28-5
| CAS No. | 2169271-28-5 |
| Molecular Formula | C16H13FN2O3S |
| Molecular Weight | 332.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 332.35 g/mol gives Vonoprazan Impurity 43 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Vonoprazan Impurity 43 (CAS 2169271-28-5) is a certified pharmaceutical impurity reference standard with the molecular formula C16H13FN2O3S and a molecular weight of 332.35 g/mol.
Based on its molecular formula C16H13FN2O3S, Vonoprazan Impurity 43 contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 332.35 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H13FN2O3S |
| Molecular Weight | 332.35 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Vonoprazan Standards
- Vonoprazan Impurity 165 (CAS CATO-C4X-1020160)
- Vonoprazan Impurity 161 (CAS CATO-C4X-1020161)
- Vonoprazan Impurity 299 (CAS CATO-C4X-1020299)
- Vonoprazan Impurity 151 (CAS CATO-C4X-1020151)
- Vonoprazan Fumarate Impurity 41 (CAS CATO-C4X-102041)
- Vonoprazan Impurity 42 (CAS CATO-C4X-102042)
- Vonoprazan Fumarate Impurity 5 (CAS 881677-11-8)
- Vonoprazan Impurity 64 (CAS 928324-73-6)
Recommended Standards
- 890099-75-9 3-(4-Phenoxybenzoyl)phenyl acetate DTXSID70641641 (CAS 890099-75-9)
- Rebamipide impurity 24 (CAS CATO-C4X-152324)
- 890099-73-7 3-(3-Phenoxybenzoyl)phenyl acetate DTXSID10641640 (CAS 890099-73-7)
- Rebamipide Impurity 33 (CAS CATO-C4X-152333)
- Leuprorelin EP Impurity A Acetate (CAS CATO-C4X-182215)
- Atrasentan Impurity 183 (CAS CATO-C4X-3347183)
- Isavuconazole Impurity 148 (CAS CATO-C4X-1236148)
- 2,5-Dibromo-1,3,4-thiadiazole (CAS 55981-29-8)
- 2-Methyl-6,7,8,9-tetrahydro-4H-pyrimido[1,2-a]pyrimidin-4-one (CAS 879499-48-6)
- tert-Butyl (3-bromopyrazolo[1,5-a]pyrimidin-6-yl)carbamate (CAS 2007920-62-7)
- 2-Chloro-4-(methylamino)-5-nitropyrimidine (CAS 89283-49-8)
- 1,4-Dihydroxy-2-nitroanthracene-9,10-dione (CAS 23743-40-0)
- Almotriptan Impurity 7 (CAS CATO-C4X-15387)
- α Bag Cell Peptide (1-9) (CAS 87549-52-8)
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