Atrasentan Impurity 183 CAS CATO-C4X-3347183
| CAS No. | CATO-C4X-3347183 |
| Molecular Formula | C19H19NO5 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Atrasentan Impurity 183 (CAS CATO-C4X-3347183), a pharmacopoeial impurity reference standard (molecular formula C19H19NO5HCl, MW 377.82 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Atrasentan Impurity 183 (C19H19NO5HCl) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 377.82 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C19H19NO5 HCl |
| Molecular Weight | 377.82 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Atrasentan Standards
- Atrasentan Impurity 131 (CAS 1058349-04-4)
- Atrasentan Impurity 132 (CAS 1058349-05-5)
- Atrasentan Impurity 133 (CAS 1058349-06-6)
- Atrasentan Impurity 134 (CAS 1058349-07-7)
- Atrasentan Impurity 135 (CAS 1058349-10-2)
- Atrasentan Impurity 136 (CAS 1058349-11-3)
- Atrasentan Impurity 137 (CAS 1058349-12-4)
- Atrasentan Impurity 66 (CAS 1058349-13-5)
Recommended Standards
- Palbociclib Impurity 68 (CAS 2444702-87-6)
- Salbutamol Impurity 111 (CAS CATO-C4X-1176111)
- Cefcapene Impurity 27 (CAS CATO-C4X-182427)
- Bis(diethylamino)phenylphosphine (CAS 1636-14-2)
- 5,7-Difluoro-2,3-dihydro-1H-inden-1-amine (CAS 173998-72-6)
- Tryptophan Impurity 18 (CAS CATO-C4X-137318)
- Tolylene-2,4-diisocyanate (CAS 584-84-9;26006-20-2)
- 4-(5-Bromopyrimidin-2-yl)thiomorpholine (CAS 1341761-16-7)
- Cefoperazone Impurity 66 (CAS CATO-C4X-114966)
- Protein Kinase C? Peptide Substrate (CAS 120253-69-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com