3-((1,1-Difluoro-2-hydroxyethyl)sulfonyl)phenol CAS 2169906-37-8
| CAS No. | 2169906-37-8 |
| Molecular Formula | C8H8F2O4S |
| Molecular Weight | 238.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-((1,1-Difluoro-2-hydroxyethyl)sulfonyl)phenol (CAS 2169906-37-8) is a high-purity analytical reference standard with the molecular formula C8H8F2O4S and a molecular weight of 238.21 g/mol.
The molecular framework of 3-((1,1-Difluoro-2-hydroxyethyl)sulfonyl)phenol (C8H8F2O4S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-((1,1-Difluoro-2-hydroxyethyl)sulfonyl)phenol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H8F2O4S |
| Molecular Weight | 238.21 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Difluoro Standards
- 3,4-Difluoro-2-(2-hydroxyethyl)benzenesulfonic acid (CAS 887585-56-0)
- 2,2-Difluoro-3-(p-tolyl)bicyclo[1.1.1]Pentane-1-carboxylic acid (CAS 2381248-01-5)
- 3-(Difluoro(phenyl)methyl)bicyclo[1.1.1]Pentane-1-carboxylic acid (CAS 2198585-38-3)
- 2,6-Difluoro-N-(5-methyl-1,2-oxazol-3-yl)benzamide (CAS 497060-15-8)
- 2,3-Difluoro-6-nitrobenzenesulfonamide (CAS 1249934-07-3)
- 2,3-Difluoro-5-nitrobenzenesulfonamide (CAS 1342407-33-3)
- 3,4-Difluoro-5-nitrobenzenesulfonamide (CAS 1803826-57-4)
- 4,5-Difluoro-2-nitrobenzenesulfonamide (CAS 1803870-61-2)
Recommended Standards
- 2-[3-Fluoro-5-(trifluoromethyl)-2-pyridyl]thioacetamide (CAS 1987078-14-7)
- 3-(3-Trifluoromethylphenyl)phenol (CAS 365426-92-2)
- 2-[3-(Trifluoromethyl)phenyl]pyridin-3-amine (CAS 886508-01-6)
- 3-(4-Trifluoromethylphenyl)phenol (CAS 365426-93-3)
- 3-(3,5-Difluorophenyl)-5-methoxybenzoic acid (CAS 1261903-90-5)
- 4-Bromo-2-Chloro-5-(trifluoromethyl)phenylboronic acid (CAS 1451393-21-7)
- 4-(2,6-Dichlorophenyl)-2-[(E)-2-(dimethylamino)ethenyl]-6-methylpyridine-3,5-dicarbonitrile (CAS 303148-14-3)
- 2-((4-(4-Chlorophenyl)-5-(4-methoxyphenyl)-4H-1,2,4-triazol-3-yl)thio)-N,N-diethylacetamide (CAS 476484-41-0)
- 7-Oxa-2-azaspiro[4.5]Decan-10-ol (CAS 1368184-76-2)
- Pazufloxacin Impurity 17 (CAS 164851-44-9)
- Piribedil Impurity 5 (CAS CATO-C4X-28135)
- 2-Bromo-6-(1H-pyrrol-2-yl)pyridine (CAS 1286278-88-3)
- 3-Fluoro-5-methyl-2-nitrophenol (CAS 1806475-40-0)
- Semaglutide Impurity 151 xTFA (CAS CATO-C4X-2226151)
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